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Grants since Jan 2018
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596 grants worth $500,453,081 have been awarded to organisations matching THE UNIVERSITY OF MELBOURNE or ABN 84002705224 since January 2018

THE UNIVERSITY OF MELBOURNE
Melbourne  $27,195,019
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency Department of Health
Program Health Workforce
Component Rural Health Multidisciplinary Training Programme
CategoryPublic Health Services Closed Non-Competitive
PurposeThe Rural Health Multidisciplinary Training Programme aims to increase the rural health workforce by supporting universities to deliver quality medical, multidisciplinary and dental training in rural communities and promote/encourage rural careers
ActivityRural Health Multidisciplinary Training Programme
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
31 May 201818 Mar 201919 Feb 201931 Dec 2020 2018-19
UNIVERSITY OF MELBOURNE
Melbourne  $1,364,055
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Global Alliance for Chronic Diseases
CategoryMedical Research Targeted or Restricted Competitive
PurposeThe states of Kerala and Tamil Nadu are currently implementing India's National Program for Prevention and Control of Diabetes, Cardiovascular diseases and Stroke. In partnership with these two state governments, we plan to adapt, integrate and evaluate the scale up of interventions that we have successfully developed and evaluated in our previous research trials to reduce cardiometabolic risk. The new research will evaluate implementation outcomes, cost-effectiveness and public health benefit.
ActivityGNT1169766 | Scaling up interventions to improve the control of hypertension and diabetes in partnership with the governments of Kerala and Tamil Nadu: Leveraging India-s national NCD program
Delivery Area Overseas FINLAND, INDIA, SINGAPORE, UNITED STATES
ApprovedPublishedStartEndBudget
31 Mar 201906 Aug 201901 Jun 201931 May 2024 2017-18
THE UNIVERSITY OF MELBOURNE
Melbourne  $1,812,005
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency Department of Health
Program Health policy Research and Analysis
Component CT Grant Activity - Low Survival Cancers
CategoryMedical Research
PurposeCT Grant Activity - Low Survival Cancers
ActivityCT Grant Activity - Low Survival Cancers
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
31 Aug 201808 Feb 201916 Jan 201915 Jun 2023 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $445,500
Address PARKVILLE 3010 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Department of Education and Training
Program International Education Support
Component Destination Australia Program
CategoryScholarships Open Competitive
PurposeDestination Australia will support both Australian and international students to study in Regional Australia
ActivityDestination Australia Program
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
30 Oct 201913 Jan 202008 Jan 202031 Dec 2023 2019-20
UNIVERSITY OF MELBOURNE
Melbourne  $21,992
Address PARKVILLE 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Agriculture and Water Resources
Agency Department of Agriculture
Program Dept Agricultural Resources
Component Science and Innovation Awards for Young People in Agriculture, Fisheries and Forestry
CategoryRural Development Open Competitive
PurposeSupport Science and Innovation Awards for Young People in Agriculture, Fisheries and Forestry
ActivityIdentification of molecular markers for subfertility in cows.
Delivery Area Multiple National AUSTRALIA
ApprovedPublishedStartEndBudget
30 Nov 201703 Jul 201809 May 201809 May 2019 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $30,377
Address Melbourne 3010 VIC AUSTRALIA ABN: 84002705224
Portfolio Foreign Affairs and Trade
Agency Department of Foreign Affairs and Trade
Program Public Diplomacy including IRGP grants
Component Australia-ASEAN Council (AAC)
CategoryPublic Diplomacy Open Competitive
PurposeLed by Dr. Lan Anh Hoang, this project seeks to develop a comprehensive and culturally sensitive sexuality education curriculum for Vietnamese secondary school students through consultative processes with government and civil society organisations in Vietnam from 2019 to 2020
ActivityDeveloping a comprehensive sexuality education program for Vietnamese secondary schools
Delivery Area Multiple VIC, Overseas AUSTRALIA, VIET NAM
ApprovedPublishedStartEndBudget
30 Jul 201927 Aug 201923 Aug 201930 Jun 2020 2019-20
UNIVERSITY OF MELBOURNE
Melbourne  $27,104
Address Carlton 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Foreign Affairs and Trade
Agency Department of Foreign Affairs and Trade
Program Public Diplomacy including IRGP grants
Component Australia-ASEAN Council (AAC)
CategoryPublic Diplomacy Open Competitive
PurposeCTN will bring eight women to MLS from Myanmar, Thailand, Philippines and Indonesia currently involved in national constitution-building to participate in a Summer School on -Constitution-Building and Peace-Building- to develop their capacities to engage in effective constitution-building processes.
Activity2019 Australia-ASEAN Women in Constitution-Building Capacity Development Program
Delivery Area Multiple VIC, Overseas AUSTRALIA, INDONESIA, MYANMAR, PHILIPPINES, THAILAND
ApprovedPublishedStartEndBudget
30 Jul 201928 Aug 201927 Aug 201915 Mar 2020 2019-20
THE UNIVERSITY OF MELBOURNE
Melbourne  $55,000
Address PARKVILLE 3010 VIC AUSTRALIA ABN: 84002705224
Portfolio Home Affairs
Agency Department of Home Affairs
Program Admin Multicultural Affairs and Citizenship
Component Fostering Integration Grants
CategoryMulticulturalism Open Competitive
PurposeSupports local organisations to assist migrants to integrate into Australian economic, social and civil life, while promoting Australian values
ActivityFostering Integration Grants Program
Delivery Area Multiple National AUSTRALIA
ApprovedPublishedStartEndBudget
30 Jan 201913 May 201903 May 201931 Mar 2020 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $35,000,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Linkage
Component ARC Centres of Excellence
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThe Centre of Excellence for Dark Matter Particle Physics will deliver breakthroughs in our understanding of the Universe through the pursuit of the discovery of dark matter particles which comprise 80% of the mass of the universe. It assembles for the first time a strong and diverse team of physicists from particle, nuclear, and quantum physics as well as particle astrophysics. It will deliver high-profile experiments using new cutting-edge technologies. The Centre will exploit the unique geographical location of the first underground physics lab in the Southern Hemisphere. The ultra'sensitive detectors and ultra-low radiation techniques will translate into a broad range of industrial applications and train a new generation of scientists.
ActivityARC Centre of Excellence for Dark Matter Particle Physics
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
29 Nov 201905 Dec 201901 Jan 202031 Dec 2026 2019-20
UNIVERSITY OF MELBOURNE
Melbourne  $3,000
Address Parkville 3010 VIC AUSTRALIA ABN: 84002705224
Portfolio Environment and Energy
Agency Great Barrier Reef Marine Park Authority
Program Portfolio Budget Statements
Component Reef Guardians Research
CategoryScientific Research Open Competitive
PurposeRGRG1900032: Interspecific hybridisation: a tool for coral reef restoration
ActivityInterspecific hybridisation: a tool for coral reef restoration
Delivery Area 3010 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
29 Nov 201824 Jun 201904 Jun 201931 Jan 2020 2018-19
UNIVERSITY OF MELBOURNE
Melbourne  $2,005,391
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency Department of Health
Program Health and Medical Research
Component 2018 MRFF Rare Cancers Rare Diseases, Unmet Need commencing 2018
CategoryMedical Research Targeted or Restricted Competitive
PurposeMantle Cell Lymphoma (MCL) has short survival and new treatments are urgently required. Our group pioneered the ibrutinib-venetoclax combination in MCL in the AIM1 study, reporting a 71 percent complete remission rate. In this proposal, we will use the knowledge from AIM to identify resistant patients apriori, and introduce the new drug navitoclax. For all patients, we will include the monoclonal anti-CD20 antibody. These results will be compared against the results of the AIM1 study.
ActivityMRF1170100 | The AIM2 Study: Genomically Guided Novel Combination Treatment of Mantle Cell Lymphoma
Delivery Area Multiple NSW, VIC, SA, QLD AUSTRALIA
ApprovedPublishedStartEndBudget
29 Mar 201926 Apr 201901 Apr 201931 Mar 2023 2018-19
THE UNIVERSITY OF MELBOURNE ACTING FOR THE AUSTRALASIAN SARCOMA STUDY GROUP
Melbourne  $1,500,000
Address The University of Melbourne 3010 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency Cancer Australia
Program Improved cancer control
Component Support for Cancer Clinical Trials Program
CategoryCancer Targeted or Restricted Competitive
PurposeClinical trials benefit the community by improving the survival of people affected by cancer, and contribute to a reduction in premature death and disability. Clinical trials are fundamental to establishing if new cancer treatments, diagnostic tests or preventive interventions are effective and they help generate evidence for best-practice cancer care.
ActivityThe development of industry-independent cancer clinical trial protocols.
Delivery Area Multiple National AUSTRALIA
ApprovedPublishedStartEndBudget
29 Jun 201805 Jul 201801 Jul 201801 Sep 2021 2018-19
THE UNIVERSITY OF MELBOURNE ACTING FOR THE PRIMARY CARE COLLABORATIVE CANCER CLINICAL TRIALS GROUP
Melbourne  $1,500,000
Address The University of Melbourne 3010 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency Cancer Australia
Program Improved cancer control
Component Support for Cancer Clinical Trials Program
CategoryCancer Targeted or Restricted Competitive
PurposeClinical trials benefit the community by improving the survival of people affected by cancer, and contribute to a reduction in premature death and disability. Clinical trials are fundamental to establishing if new cancer treatments, diagnostic tests or preventive interventions are effective and they help generate evidence for best-practice cancer care.
ActivityThe development of industry-independent cancer clinical trial protocols.
Delivery Area Multiple National AUSTRALIA
ApprovedPublishedStartEndBudget
29 Jun 201805 Jul 201801 Jul 201801 Sep 2021 2018-19
ASIALINK, THE UNIVERSITY OF MELBOURNE
Melbourne  $8,800
Address Carlton 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Foreign Affairs and Trade
Agency Department of Foreign Affairs and Trade
Program Public Diplomacy including IRGP grants
Component Australia-Korea Foundation
CategoryPublic Diplomacy Open Competitive
PurposeWe will take a small delegation including an Australian craftsperson and creative craft curator/director to the Cheongju Craft Biennale in 2019 and to invite a Korean craftsperson to come to Australia on exchange in 2020.
ActivityCheongju Craft Biennale Exchange
Delivery Area Overseas KOREA, REPUBLIC OF
ApprovedPublishedStartEndBudget
29 Jul 201907 Aug 201901 Sep 201930 Jul 2020 2019-20
MELBOURNE LAW SCHOOL
Melbourne  $27,661
Address The University of Melbourne 3010 VIC AUSTRALIA ABN: 84002705224
Portfolio Foreign Affairs and Trade
Agency Department of Foreign Affairs and Trade
Program Foreign Affairs and Trade Operations
Component Ad hoc/One-off
CategoryOverseas Advocacy
PurposeHost a ten day, structured study tour for Asian death penalty litigators in Melbourne. The project aligns with Australia's Strategy for Abolition of the Death Penalty, and supports its focus on the Indo-Pacific Region.
ActivityDeath Penalty Litigation Study Tour
Delivery Area 3010 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
28 Nov 201808 Jan 201918 Dec 201830 Jun 2019 2018-19
UNIVERSITY OF MELBOURNE
Melbourne  $19,572
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Industry, Innovation and Science
Agency Department of Industry, Innovation and Science
Program Supporting Science and Commercialisation
Component Science for Australia's Future - Inspiring Australia
CategoryScientific Research Open Competitive
PurposeThroughout National Science Week and the preceding week, "The Art of Science: Maths, Music and Me"- will reveal the rich mathematics behind music in unique presentations interweaving stories, performance and equations. It will showcase the possibilities and applications of mathematics in life and art. Educational and inspiring, the audience will be taken on a journey through popular music revealing the rich mathematics behind it.Presentations will take place in metropolitan and regional areas.
ActivityThe Art of Science: Maths, Music and Me
Delivery Area 3010 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
28 Mar 201904 Apr 201901 Apr 201929 Apr 2020 2018-19
UNIVERSITY OF MELBOURNE
Melbourne  $939,630
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Industry, Innovation and Science
Agency Department of Industry, Innovation and Science
Program Supporting Science and Commercialisation
Component Australia-China Science and Research Fund
CategoryScientific Research Open Competitive
PurposeGraphene is one of the most exciting new materials to have emerged in the last 50 years. It opens up potential new products across a wide range of optics, electronics, spectroscopy and energy applications. Under the Australian China Science and Research Fund, the Joint Research Centre will enable Chinese and Australian scientists to work together on the development of the flexible electronics applications including low-cost flexible solar cells for portable power generation, low cost perovskite solar cells for the Australian market and new near-infra-red technologies including photodetectors and night time imaging systems.
ActivityJoint Research Centre for Flexible Graphene Electronics
Delivery Area 3010 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
28 Mar 201915 Jul 201928 Jun 201908 Oct 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $586,900
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to determine if improving teacher knowledge and practice of mindfulness in the classroom, can lead to better child attention and school functioning outcomes during the early primary school years. Mindfulness is an approach that aims to improve attention, self-regulation, mental health, and cognitive functioning. Expected outcomes include new knowledge as to whether mindfulness can be integrated into classroom practice, how to best implement it, student benefits and cost-effectiveness. Findings will inform schools as to whether this approach can support students in making a positive transition to primary school that can place them on positive academic and well-being pathways and lead to benefits in their adulthood.
ActivityDoes a teacher-led mindfulness intervention improve student outcomes-
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $344,741
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to explore the post-war architectural, rural and industrial landscapes of Australia as shaped by the labour of displaced persons. Migrants after the Second World War were critical to the spatial making of modern Australia. Major federally-funded industries driving post-war nation-building programs depended on the employment of large numbers of war-displaced persons. While the immigrant contribution to nation-building in cultural terms is well-known, its everyday spatial, architectural and landscape transformations remain unexamined. This project aims to bring to the foreground post-war industry and immigration to comprehensively document a how Australia has uniquely shaped its built environment.
ActivityArchitecture and industry: the migrant contribution to nation-building
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $361,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis proposal aims to assess the impact of geographical and genetic isolation of the Australian Indigenous population on adaptive and innate immune systems. The project will use novel DNA sequencing approaches to generate the high resolution sequences of two genetic loci that regulate innate and adaptive immune responses, the major histocompatibility complex locus and the killer cell immunoglobulin-like receptor locus. In an initial screen, distinct variants and combinations of these genes were identified. This project aims to interrogate how variation in these critical genes impacts on the function of cytotoxic lymphocytes, providing insights into the evolutionary drivers of immune recognition mechanisms.
ActivityInvestigating the evolution of innate and adaptive cellular immunity
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $304,550
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to bring European and Chinese art history into dialogue. It explores the early Italian Renaissance in the larger geopolitical context of Mongol Eurasia and the Yuan Empire, to address the questions of influence, contact, and exchange. In reframing the development of early European art as a fundamentally cross-cultural phenomenon, this project aims to offer a better understanding of the roots of our own global visual culture. The project will benefit and enrich the study of cross-cultural contact and exchange in art history as a larger field, leading to the re-examination of art in the Australasian region.
ActivityEurasian exchange and artistic transformation in art
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $380,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to provide efficient, distributed resource allocation algorithms that can perform satisfactorily within time limits imposed by real-time systems. Real-time Internet of Things (IoT) devices will play a significant role in future transport technologies, such as autonomous vehicles and smart traffic management, and will place significant demands upon distributed computing systems to provide timely information updates. The computing challenge is to provide reliable, accurate and timely information to IoT devices. The outcomes of this project will directly be beneficial to a variety of IoT applications in transportation, autonomous vehicles, and smart cities. The valuable engineering insights and novel algorithms will support industry, government, and practitioners for future real-time IoT design and deployments.
ActivityReal-time internet of thing algorithms with performance guarantees
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $300,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to advance our understanding of knots and 3-dimensional spaces, which arise naturally in fields as diverse as physics, computer graphics, chemistry and biology. Recent ideas from quantum field theory link physics to topology in dimensions 3 and 4, leading to powerful invariants of knots and 3-dimensional manifolds that include the Jones polynomial and the 3D-index. This project aims to resolve key questions relating these quantum invariants to classical topology and geometry. The project will have a major impact in low-dimensional topology, and lead to deep and unexpected connections between mathematics and mathematical physics.
ActivityClassical and quantum invariants of low-dimensional manifolds
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $391,546
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to develop new biostatistical methods for addressing complex analytic questions that arise in studies of the causes of health, social, educational and other outcomes in the course of human life. These questions concern the pathways that explain how intermediate factors contribute to a statistical relationship between a probable cause of a later outcome. Mathematical and statistical innovation is needed to address them. The expected outcomes include a suite of novel methods designed to evaluate the impact of intervening to modify causal pathways, while also accommodating common complexities of data such as incompleteness. This project should provide major benefits to studies in public health, social sciences and economics.
ActivityStatistical methods for modelling the pathways between cause and effect
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $362,116
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to generate new knowledge of institutional reform in the late Roman republic and the relevance of reform as a concept in ancient Rome. By analysing how Romans spoke and wrote about reform and examining a variety of particular reform efforts, the project seeks evidence of a Roman reform discourse and reform processes capable of producing structural change. Expected outcomes include fresh understanding of republican governance and an alternative to the conventional view that the republic fell because of its inability to reform itself. This project should benefit the study of Roman history and foster dialogue with interdisciplinary scholarship which has questioned the reformability of ancient societies; it thus also informs the understanding of reform in contemporary societies.
ActivityReforming the Roman Republic
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $401,980
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to undertake a comprehensive and comparative investigation of governance and enforcement in the charitable sector in Australia. Public trust in the charitable sector has been damaged by governance failures, particularly in religious contexts, exacerbated by the sector's complex and incoherent governance system. As yet, there has been limited academic consideration or empirical analysis of the effectiveness of the governance and regulatory framework of the sector or concrete reform proposals. This project aims to undertake comparative analysis and empirical research of these aspects, and to develop proposals for effective law and policy reform. This is expected to strengthen and maximise the sector's capacity to contribute to the social and economic life in Australia.
ActivityRestoring public trust in charities: reforming governance and enforcement
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $370,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to investigate the origins and labour market consequences of gender differences in willingness to perform low-promotability tasks. The design of practices and institutions that can close gender gaps in the labour market and promote the advancement of the highest quality workforce in organisations requires information about the factors that affect career advancement. This project will study the allocation of tasks that do not enhance prospects for promotion. The project will provide new insights regarding how organisations and the government can design programs to reduce the under-representation of women in leadership positions and in traditionally male-dominated fields.
ActivityWomen, task allocations, and advancement in the labour market
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $195,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to analyse Australian welfare policy from the end of the Chifley government in 1949 to the end of the Howard government in 2007. The project intends to generate new understandings about the challenges facing the income support system, the key dynamics of policy reforms such as Medicare and Superannuation, and the -exceptionalism- of the Australian model. Expected outcomes include a new database based on time'series data concerning the core income support systems from 1950 to 2020. Intended benefits include a better understanding of the sort of welfare reform needed to pay for major social risks of unemployment, poverty, aged care, disability and the needs of children.
ActivityAustralian welfare policy, 1950 to 2007: continuity and disruption
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $469,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to examine the mechanisms that explain the origin of the matter-antimatter asymmetry of the universe.-Particle physics seeks to understand the fundamental constituents of matter and their interactions. This project will use the new Belle II detector at the SuperKEKB collider in Japan to address the origin of matter-antimatter asymmetry, and why fundamental matter particles have enormous mass differences across the three generations. The project aims to develop new data mining techniques to fully exploit the data from the Belle II experiment, placing Australian researchers in a position to make a major discovery of new physics phenomena in order to complete the theory of the universe at the smallest scale.
ActivitySearching for new phenomena in semileptonic B decays with Belle II
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201819 Dec 201918 Dec 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $596,040
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to improve our understanding of how the heart develops after birth and the molecules that control this process. Recent advances in tissue engineering have opened up opportunities for the generation of synthetic tissues but these studies have also highlighted a fundamental knowledge gap in our understanding of how complex tissues mature to prepare for life as an adult. Much is known about the molecules that control early embryonic development but little is known about the molecules that control maturation after birth. This project aims to build new knowledge that is expected to improve our ability to generate mature heart muscle cells for stem cell applications, tissue repair and regeneration.
ActivityMolecular control of postnatal heart development.
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $487,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to understand how thermosensing mechanisms in plants result in transgenerational change, and potentially adaptation to climate. Exploiting the recent discovery of the thermosensor phytochrome B, this project will decipher the molecular cascade which, either through long-distance communication or through persistence of an epigenetic state in the cell lineage, could lead to a trans generational memory in plants helping with climate adaptation. This project will unravel novel molecular mechanisms, which have the potential to pave the way for designing new climate-proofing solutions to cope with temperature uncertainty.
ActivityThe transgenerational effect of thermosensing in plants
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $437,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to improve our understanding of cell types, lineage relationships, cell-cell interactions and morphogenetic processes in human kidney development. Investigators have developed a method to produce multicellular kidney organoids from human pluripotent stem cells (hPSC). This project will use gene-edited reporter hPSC lines and high-res imaging to study the lineage relationships and morphogenetic mechanisms of these human kidney organoids. This project aims to validate the origin of nephrons in kidney organoids, study the origin of the renal stroma versus the nephron progenitor, and monitor nephron patterning and segmentation at a clonal level. This will improve our knowledge of human kidney development in a human model.
ActivityStudying early human kidney development using stem cells
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $360,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to produce an original account of property law that will connect it to place and human relationships. Property is at the centre of contemporary social life and law, yet it is often separated in legal scholarship from the human and natural worlds it structures. Using innovative analytical techniques and a grounded consideration of the functions and effects of property, the objective of the project is to produce an understanding of property as habitat that is both sensitive to place and adapted to social conditions. Expected benefits include a responsive understanding of property that is better able to address the challenges of Australian society into the future.
ActivityProperty as habitat: reintegrating place, people, and law
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $474,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to investigate how cargo is trafficked to the right destination inside cells. The project will investigate the trafficking routes and the critical machinery required. This project is expected to generate fundamental new knowledge in the areas of cell biology and immunology. Expected outcomes of this Project include scholarly publications and highly-trained personnel in cell biology and immunology. This project will provide significant benefits such as advances to fundamental knowledge, training for higher research degree students, opportunities for the biotechnology sector and strengthened international (research collaborations.
ActivityTrafficking inside the cell for effective immunity
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $356,196
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to generate data identifying the nature, circumstances and impacts of sexual and intimate partner violence against female international students in Australia. A range of cultural, social and structural issues may increase the vulnerability of female international students to gendered violence, leading to serious impacts on health and well-being. Yet, little is known about their experiences or how best to support them. This project intends to increase the safety of female international students by identifying their risk and protective factors, exploring their experiences and support requirements, and developing best-practice responses. Outcomes of this project include a new conceptual model and guidelines for service providers.
ActivityInternational students' sexual and intimate partner violence experiences
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $510,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to harness the ability to control the fundamental interactions which limit the precision of a diamond quantum sensor, enabling more sensitive magnetometry. Quantum sensors are unveiling new insights into nano'scale phenomena. Single atom defects in diamonds have been at the forefront of this revolution in nano'scale sensor technology. A unique capability, spinning diamond quantum sensors at up to 500,000 rpm, fast enough that quantum properties of the defects are preserved during a cycle has been established. This project will address the long'standing problem of nano'scale solid-materials characterisation using rotationally-enhanced quantum magnetic resonance spectroscopy.
ActivityControlling spin coherence with rotation
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $336,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to analyse socio-cultural benefits and risks in the two significant environmental markets of carbon and water across three sites in Australia and Timor-Leste. Research into market-based policies to manage significant environmental issues is yet to fully consider socio-cultural dimensions. This project intends to document local community producers, distant investor and consumer perspectives, and incorporate these perspectives into methods for improving the operation and impact of these expanding markets. By undertaking the first systematic comparison across resources and sites, the project expects to fill a key gap in environmental scholarship and contribute to international strategies to improve social and environmental outcomes in market-based environmental policy.
ActivitySocial implications of market-based policy instruments for carbon and water
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $448,955
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to synthesise and investigate metal-based molecules that can be reversibly switched between forms with different physical properties, such as colour or electrical conductivity, upon exposure to heat, light or electrical potential. The project expects to develop compounds that offer physical properties relevant for deployment in advanced materials or nanodevices. Expected outcomes of this project include elucidation of chemical routes to tuning the switchability and candidate compounds for future applications. As well as achieving important advances in fundamental chemistry, this project should provide significant benefits, such as novel materials for molecular electronics/spintronics, photoresponsive devices or sensors.
ActivityHarnessing redox-active ligands in functional metal complexes
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $300,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to expand the theory of polynomials and develop generalised polynomial families using connections to affine and toroidal algebras.-Many combinatorial and computational problems in pure and applied mathematics as well as mathematical physics can be solved using polynomials in many variables, such as Macdonald polynomials. This project is anticipated to address the current difficulty of implementing symmetric and non'symmetric polynomials in symbolic algebra packages by developing completely new algorithms. New understanding from the project is expected to facilitate challenging computational problems of measurable quantities in quantum systems.
ActivityMatrix product multi-variable polynomials from quantum algebras
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $410,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to develop the theory and supporting research tools to investigate how, where, and why people engage in digital emotion regulation. Individuals often use digital technologies to shape their emotions, yet social norms often cast such technology use as disrespectful or distracting. The discrepancy between the practice and perception of digital emotion regulation may be due to the lack of a systematic understanding of this behaviour. The project will inform the debate about technology use and its impact on work, education and interpersonal relationships. Additionally, the created knowledge will inform policy-makers, designers, and end-users about how technology use is perceived, as well as effective use of technology in everyday settings.
ActivityConceptualising and measuring digital emotion regulation
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $370,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to develop novel membrane support materials and novel membrane structures to enhance chemical separation processes. These materials can be used in desalination and water treatment, reducing the resistance to water flows. In turn, this will reduce the energy required to produce fresh drinking water for Australians, as well as the cost. The approach will also be applied to carbon dioxide capture from flue gas streams, increasing the energy efficiency of these processes, so that they can become economically viable. The project has the potential to develop localised manufacturing operations to produce these materials, adding value to Australian manufactured products.
ActivityNovel membranes and membrane structures using electrospinning
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $864,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Linkage
Component Linkage Infrastructure, Equipment and Facilities
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project will secure membership for Australia's ongoing participation in cutting-edge experimental particle physics, which explores the fundamental nature of matter and energy and how the universe works. The two frontiers of the field are the energy frontier at CERN's Large Hadron Collider and the intensity frontier at Japan's SuperKEKB collider. By providing the basic contributions required for Australian membership of these two key programs and capitalising on decades of work and accumulated expertise, significant project outcomes and benefits are expected. These include access for Australia to advanced international research facilities, training of the next generation, and a rich scientific program.
ActivityEnabling the future of the Australian collider physics program
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2020 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $445,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to advance understanding of the impacts of sea-level rise and associated policy responses on the everyday lives of island communities. Focusing on village relocation in Fiji and fortification and land reclamation in the Maldives, the project will analyse people's changing everyday experiences and practices. The project seeks to enable international and interdisciplinary collaborations, and to produce new knowledge on the opportunities and challenges of diverse policy responses to sea-level rise. The project's findings will be beneficial for countries facing the threat of sea-level rise, as well as national governments and international agencies that support and fund climate adaptation.
ActivitySea-level rise and everyday lives in small island states
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $351,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to improve reliability and accuracy of wearable devices by developing a new set of computationally efficient algorithms. Wearable devices can be very effective in remote and continuous monitoring to detect short or bursty anomalous events. Present devices are unable to detect such events effectively due to limited capability in processing short length signal. This project will provide computationally efficient algorithms for signal quality analysis and enhanced feature extraction methods in resource constrained wearable devices. This will improve the reliability and performance of wearable devices for adoption in intelligent decision-making systems.
ActivityNew entropy measures of short term signals for smart wearable devices
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $388,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to investigate the conceptualisation, creation and promotion of new cities in Australia since the mid-20th century. The project expects to generate new knowledge in the area of urban planning and architectural history, leading to new understandings of community engagement with planning and architecture and dialogue on decentralisation, housing affordability and metropolitan primacy. Expected outcomes of this project include contribution to the national conversation regarding political vision for large'scale infrastructure through a book, short film and media engagement on the topic. This project should provide significant benefits to community dialogue on issues of heritage, housing and environment.
ActivityAustralia-s new cities: past, present and future
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $441,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to use matchstick grasshoppers as a model system to develop strategies and protocols for maximising the adaptive potential of species when movement of individuals or genes is required. Biodiversity management increasingly requires translocation or targeted gene flow to maintain genetic diversity, raising the issue of disrupting local environmental adaptations. Matchstick grasshoppers are extremely well understood genetically, are highly amenable to experimental investigation, and include populations and species threatened by habitat destruction. This project will generate novel conservation tools for the focal species as well as empirical precedents for resolving the problem of environmental mismatch in translocation.
ActivityEnvironmental mismatch in invertebrate translocations for conservation
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $410,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to evaluate the environmental impacts of the spatial concentration of firms. Taking advantage of increasing availability of geo-referenced economic data, the project will evaluate the environmental costs and benefits of policies to promote industrial clusters in China, India, and Colombia. The collected datasets will match trends in firm-level emissions imputed from accounting data to ambient pollution measures derived from ground monitors and satellites. This project will investigate the interactions between economic growth and industrial emissions, and provide recommendations based on a better understanding of whether industrial clusters mitigate or exacerbate local and global emissions from manufacturing.
ActivityThe environmental costs and benefits of special economic zones
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $437,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis proposal aims to develop a framework for statistical modelling that integrates across spatial scales and disentangles the processes of environmental tolerance, biotic interactions and dispersal. Understanding the processes that drive species distributions and ecological communities is central to ecology and environmental management. This knowledge can be used to anticipate the impacts of environmental change on ecosystems, and the likely benefits of interventions. Current statistical models limit the data that can be used and the ecological questions that can be answered. This project expects to improve our ability to predict species distributions under changed environments given interacting species and dispersal across the landscape.
ActivityIntegrating niches, interactions and dispersal in species distribution models
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201819 Dec 201918 Dec 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $290,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to provide a new understanding of the emergence of classical tragedy by reassessing how classical Latin drama was revived in 14th century Europe after a long period of neglect. Classical tragedy, which incorporates the myths of the Graeco-Roman world in its fabric, was virtually unknown from late antiquity until the high middle ages when the tragedies of Seneca became popular. In the early 14th century, commentaries by Albertino Mussato and Nicholas Trevet allowed a new readership access to these complex ancient works; this analysis also provides new insights into trends of popularity across the ages.-Using recent advances in digitisation technology and scholarship, the project will establish a model for research into the history of the book, the image, and text.
ActivityThe rediscovery of Senecan tragedy in 14th century Europe
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $531,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to answer questions about how plants can sustain their growth on salty soils. Plant-derived products constitute a pillar for our society. However, crop yields may be severely penalised due to unfavourable growth conditions, including soil salinity. This is particularly relevant for Australia as a large fraction of its arable land is affected by salt. This project aims to use molecular and cell biology techniques to resolve mechanisms of how the synthesis of cellulose, which constitutes the bulk of a plant's biomass, is maintained in plants during salt stress. This project has potential for climate change mitigation, enhanced plant biomass production and improved fuel security.
ActivityCan we engineer plants to grow on salty soils-
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201819 Dec 201918 Dec 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $181,602
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to explore how photography and film transformed understandings of human sexuality. By analysing how and why doctors and scientists shifted their attention from textual to visual evidence, the project will contribute to understandings about how images have been used historically to create medical norms and communicate scientific knowledge to broad audiences. Focusing on Germany as the international centre of early twentieth-century sex research, the project will examine how the turn to visual evidence had a transnational impact by paving the way for post-war researchers such as Kinsey, Masters and Johnson, and for a better understanding of the history of human sexuality in Australia.
ActivityVisual evidence: transforming modern sex research (1880s - 1930s)
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $339,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to develop methods for identifying poor quality data in biological databases. Research in biomedicine is underpinned by massive databases of biological data. Data quality is largely managed through manual curation, but automated methods to assess quality are critically needed. This project expects to develop a suite of computational tools for assessing biological data quality, utilising an innovative approach based on network analysis of database record connectivity. These tools will enable quantifying data quality at scale. Researchers, evidence-based decision-makers in biomedicine, and the analytical or predictive tools that use this data will make more reliable inferences and decisions.
ActivityAutomated assessment of data quality in biological knowledge resources
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $405,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to explore the architecture of terabit data transport using self-coherent detection that addresses the tight constraints of power, space and cost in data centres. The project expects to create new knowledge in coherent detection based on optical equalisation rather than conventional power-hungry electronic equalisation. Expected outcomes of this project include advanced architecture of polarisation effect equalisers and all-optical equalisation algorithms as well as enhanced international collaboration with top experts in optical communications. The outcomes will contribute to maintaining Australia's high reputation in the ICT arena.
ActivitySelf-coherent detection for data centre
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $430,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to develop ultra'sensitive detector technology essential for SABRE, a world-wide experiment with detectors in both the Northern and Southern Hemispheres which are operated together to directly detect the dark matter halo of our Milky Way galaxy. Dark matter makes up nearly five times more mass in the universe than everything we can see, yet it has never been detected in the laboratory. SABRE South will be installed in the Stawell Underground Physics Laboratory in a goldmine in Victoria, Australia. Dark matter is not the only thing SABRE can detect. The project will measure all possible types of naturally occurring radiation, from space, the surrounding rock, and the detectors themselves, that can blind SABRE to dark matter.
ActivityMeasuring critical background in the Australian search for dark matter
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $153,088
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to undertake the first systematic investigation of secrecy in everyday life. Secrecy is often vital in professional and personal life, but current scientific understanding of the costs and processes of secrecy is limited. This project proposes using innovative methodologies to estimate the psychological costs of secrecy and test an intervention to reduce these costs. Expected outcomes include developing theory, advancing methodology, and building research capacity in supporting exceptional scholars. Significant benefits include educating community members about how to combat the harmful effects of secrecy.
ActivityUnderstanding secrecy in everyday life
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $382,656
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to develop phylogenetic approaches to harness the potential evolution of bacterial and virus pathogens data and to improve early detection of infectious outbreaks. Genome surveillance programs consist in routine sequencing of particular organisms to track their evolution over time. Such programs currently exist for important bacterial and virus pathogens. This project expects to develop computational methods to improve our understanding of pathogen outbreak emergence and infectious spread using genome data. This project will expand our knowledge base and research capability in the evolution and epidemiology of infectious agents, and aid in the prevention and control strategies of infectious disease benefiting the research priorities of food and health.
ActivityPhylogenetic methods for genome surveillance of microbial pathogens
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $409,256
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to advance the science of emotion by resolving a fundamental paradox regarding the relationship between emotion dynamics and well-being. Emotion dynamics are reliably associated with psychological well-being. However, emotional flexibility and stability have been identified as important for healthy functioning. This project aims to resolve this paradox by applying cutting-edge statistical techniques to model emotion dynamics in daily life, as captured using smartphones. The project will develop a comprehensive theory of the relationship between emotion dynamics and well-being. This project will contribute to fulfilling the potential of mobile assessment methods for tracking and improving mental health and well-being.
ActivityEmotion dynamics and well-being
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $372,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to design and study DNA printing to manufacture long strands of DNA using simple but elegant fundamental non-enzymatic chemical reactions. Gene therapy is one of the most rapidly growing therapies in modern medicine but it is prohibitively expensive for the average person. Current methods of artificial gene synthesis are complicated with commercial DNA synthesis only supplying short DNA strands. The project outcomes will lead to a stable template directing the chemical reactions for DNA printing. This new approach will make life'saving gene therapy cheaper and more widely available for future generations and provide economic, and social benefits to all Australians.
ActivityDNA printing on a synthetic polymer template
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $499,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to increase our understanding of the role of glycine receptor-mediated signalling and its metabolism in the amino acid sensing capacity of mTORC1, a key enzyme regulating muscle protein synthesis.-Ageing is associated with a progressive decline in skeletal muscle mass, weakness, and impaired regeneration after injury. Impaired anabolic signalling after food intake has been proposed as a key contributor, yet the metabolic pathways responsible for nutrient sensing and regulation of protein synthesis remain unresolved. The project will assess defective amino acid sensing and protein synthesis in old mammals, identifying the role of glycine signalling in these processes. The project expects to underpin development of muscle'specific modulators of muscle homeostasis with broad relevance to Australia's ageing population.
ActivityAge-related mechanisms of amino acid signalling in skeletal muscle
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $600,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to address the fundamentals and applications of regulating micropore accessibility. It has long been known that some highly adsorbing molecular sieves suddenly become inaccessible to gases below certain temperatures. Following a recent breakthrough in elucidating the mechanism of such temperature-regulated guest admission, this project will explore electrical regulation of micropore accessibility in conjunction with developing new mechanisms, materials, and control tools for applications, including tunable molecular sieves, valves and gas encapsulation devices. The outcomes of this project will generate new knowledge in the active manipulation of the admission and release of guest molecules in/out of microporous materials, and establish new expertise and capabilities that can advance gas separation, storage and sensing technologies. It is expected that this project will contribute to the long term benefit in low emission energy supplies and Australia's natural gas industry, improve the separation efficiency of our chemical industry, and boost the development of the hydrogen economy.
ActivityRegulating guest transport in microporous materials by electric field
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $421,140
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to create the computational models and methods needed to advance current understanding of musculoskeletal function during movement. Humans must maintain their capacity to move in order to maintain quality-of-life. Predictive modelling is potentially the most powerful approach for understanding musculoskeletal function during movement. Current computational methods are too slow and unreliable to deliver predictive simulations of movement using realistic models of muscle and joint anatomy. This project expects to create the next generation of methods and algorithms needed to enable predictive modelling of movement. Predictive simulations will provide new insights into how muscles stabilise and control movements of the spine, pelvis and lower limbs during daily activities such as walking.
ActivityFinal frontier in computational modelling of movement
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $340,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to discover how animals use nanophotonic structures to manipulate near infra-red light for thermal control and visual information. Almost nothing is currently known about the mechanism, function and evolution of near-infrared properties in animals, despite their potential importance for maintaining body temperatures within the critical thermal limits for survival. The project uses multidisciplinary techniques from optical physics, physiology and evolutionary biology to reveal near-infrared adaptations in socially and economically important Christmas beetles. The intended outcomes include a bio-informed blueprint for a new class of functional nanomaterials that enhance energy efficiency.
ActivityHow beetles harness near-infrared properties to enhance energy efficiency
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $580,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to delineate the cellular interactions involved in the initiation of immune responses by utilising advanced in vivo imaging. Adaptive immunity in vertebrates functions via the acquisition of signals by immune cells via complex interactions with other immune cells, yet these exchanges are difficult to observe and define. This project expects to provide insights into the mechanisms that underpin effective cell-mediated immune responses. The expected outcomes are to generate fundamental new knowledge about immune responses and enhance capacity to study the immune system. This could benefit future development of new vaccines and therapies to improve health.
ActivityA cellular hub for the organisation of T cell priming
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $410,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to improve modelling of the genetics underlying complex traits. The project will develop and test models for using genome-wide genetic data to investigate how much heritability (genetic effect) underlies traits of interest, where it lies in the genome, and how much of it is shared across traits. The new models will be implemented in statistical algorithms in a freely-available software package. This project expects to increase understanding of biological mechanisms, the efficiency of genetic association analyses and the accuracy of genomic prediction, including the effects of interventions. The project will adapt human models to a wider range of organisms, in particular bacteria.
ActivityImproved models to understand the genomic architecture of complex traits
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jun 201931 May 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $0
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to address the increasing concentration of greenhouse gases in the atmosphere and the limited nature of fossil fuel reserves, by accelerating the development of technologies capable of producing liquid fuels from atmospheric carbon dioxide. The project expects to generate new knowledge in the area of advanced materials for renewable energy applications. It will use an innovative experimental material optimisation approach, coupled to mathematical modelling techniques. Expected outcomes include an enhanced capacity to develop electrochemical devices that transform carbon dioxide into liquid alcohol fuels, which could reduce the carbon footprint of transport activities without the need for further extensive infrastructure. Technologies to convert carbon dioxide into a valuable product will provide an economic incentive to reduce emissions, and will increase the commercial value of carbon capture systems currently under development in Australia.
ActivityGas diffusion electrodes for conversion of carbon dioxide into fuels
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201901 Jan 2019 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $418,085
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to construct and describe three important integrable systems and to produce new significant results in representation theory and mathematical physics. The focus of the project is the theory of integrable systems, a breakthrough area in modern mathematics, and it will use tools from geometric representation theory to study the interrelation between geometry and mathematical physics. Originating from string theory, the project will not only provide a deeper understanding of the universe, it will also train young mathematicians and other highly qualified individuals with the potential to make a significant impact to technology, security, and the economy though their specialised skills.
ActivityIntegrable systems from gauge theories
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201908 Apr 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $390,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to use new RNA'sequencing technology to identify genes important for differentiation of several major enteric neuron subtypes. Proper development and function of the digestive tract is crucial for good health. Gastrointestinal function relies on the co-ordinated activity of neural circuits in the enteric nervous system. This project will advance Australia's knowledge base and research capabilities in the field basic developmental neuroscience, by innovative use of Next Generation RNA'sequencing technology to investigate enteric neuron subtype differentiation. The project outcomes include the generation of neuron subtype specific progenitors from na-ve stem cells, which will in the longer term have significant health benefits, as gastrointestinal dysfunction is a large health and economic burden in Australia.
ActivityGenes underlying enteric neuron subtype differentiation
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Nov 201931 Oct 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $382,974
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to investigate the inherited family secrets, stories, and memories that inform understandings of Australian colonial history. The histories told in schools and museums shape national identity and can affect Indigenous'settler relations. This project expects to generate new knowledge about the histories told or concealed within families, and how they influence people's political views. It will benefit individuals and communities working toward national healing by creating knowledge about how views are created, fixed, and altered over time.
ActivityFamily secrets and intergenerational memory in Australia
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201830 Jul 201929 Jul 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $422,232
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to map the brain circuits controlling fluid and salt intake using innovative genetically encoded techniques, which enable precise targeting and manipulation of select neuronal populations. Expected outcomes of this project include constructing detailed maps of the brain circuits for fluid and salt intake by tracing multiple nodes in the network, characterising neuronal populations, and precisely defining their functions. This should provide significant benefits including understanding the brain regions controlling fluid and salt intake which are essential for maintaining fluid homeostasis, and providing a framework for investigating the neural circuits underlying other complex behaviours.
ActivityMapping the neural circuits which control water and salt intake
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jul 201930 Jun 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $410,856
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to generate detailed information about the processes and impacts of regional youth engagement. This project addresses the need for key regional areas in the country whose youth populations are in decline to have more effective policy strategies in place to engage with their existing young people, stay engaged with young people who leave, and re-engage young people who return. Expected outcomes include theory development, policy recommendations, and new artistic methods of knowledge transfer with the intention of providing stakeholders with much-needed evidence to inform policy initiatives.
ActivityEngaging youth in regional Australia
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $450,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to address the problem of the existence of cosmological dark matter. The interactions of dark matter particles with regular matter will be investigated using complementary techniques which combine information from particle experiments and astrophysical observations. The expected outcomes include major theoretical advances, which will provide an important guide for future experimental searches, and contribute to the development of a world-class dark matter research capacity in Australia. Significant benefits include high level training of students and early career researchers, contributing to a highly skilled STEM workforce.
ActivityDark matter interactions
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $520,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to delineate how a protein modification that consists of the addition of a small sugar to cellular proteins, known as O-GlcNAcylation, provides a link between metabolism and complex cell functions. The model for these studies is a cell type of the immune system known as dendritic cells. Upon encountering pathogens these cells undergo metabolic changes that increase the rate of O-GlcNAcylation of proteins involved in immune responses, altering their function. This project will study how O-GlcNAcylation works and is regulated. The project expects to develop new technology and provide high-level training, increasing the competitiveness of the strategic biotechnology sector in Australia
ActivityA novel link between metabolism and host defence
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $343,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to quantify the cumulative impacts of harvest and climate change across marine fishes and ecosystems. The project expects to generate new knowledge in this area by coupling the rich biological information archived in fish ear bones, with targeted multi-generation experiments and predictive modelling. Expected outcomes include fundamental insights into how human-induced environmental change affects fish growth and maturation, and a subsequent critical evaluation of the sensitivity of fisheries models to trends in these life-history traits. This should provide significant benefits to fisheries and ecosystem management, ensuring they remain productive and resilient in a time of rapid environmental change.
ActivityUnderstanding climate and harvest induced changes in fish life histories
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $380,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to produce validated methods for creating human-centred explanations of decisions made by artificial intelligence (AI). Trial deployment of AI devices has resulted in the requirement for explanations of how AI makes decisions, where developed AI systems gave insufficient consideration of how decision logic would be explained to people. This project positions 'explainable AI' within the intersection of human-computer interaction, computer science and cognitive psychology. The expected outcomes of this project are new methods, models and algorithms for explaining different types of AI models to people. This project should result in improved understanding and trust of decisions made by AI systems, mitigating some societal concerns about AI-based decision making.
ActivityExplanation in artificial intelligence: a human-centred approach
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $425,291
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to identify, evaluate and develop theoretical and practical ways in which intercultural music engagement can facilitate social cohesion and enhance community resilience and intercultural empathy. There is growing evidence that music is a powerful stimulus for wellbeing and interpersonal connection and it is increasingly applied to promote intercultural understanding. This project will use detailed observational, participatory and experimental strategies to elucidate the psychosocial processes underpinning intercultural music engagement, isolating variables that promote social cohesion. The project will develop best practice guidelines for organisations seeking to use cultural exposure and interaction to promote positive multicultural experiences.
ActivitySocial cohesion and resilience through intercultural music engagement
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $0
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to identify new physics in quantum magnets and emergent phenomena in solids where the electrons are strongly coupled and intertwined in a complex manner. As a consequence, quantum effects are dramatically enhanced and, in certain situations, force the electrons to split into different exotic particles. Expected outcomes of this project include identification of suitable physical systems, candidate materials and appropriate conditions required for the experimental observation of this phenomena with neutron scattering methods. Such particles host an unexplored potential for future electronic devices and might be key for next generation technologies. The advanced materials and exotic particles identified in this project will inform the development of next generation technologies, becoming the quantum bits in future quantum computers.
ActivitySearch for spin liquids and novel physics of strongly correlated electrons
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201901 Jan 2019 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $360,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to map out the complex evolution of the Earth's ocean ecosystems and oxygenation using marine carbonates. The oxygenation of Earth's surface is one of the most profound processes to shape the planet, affecting all biological and geological systems. However, uncertainties remain in the timing of oxygenation and how it relates to the evolution of life. This project will develop our understanding of how Earth has remained habitable through significant intervals of environmental change. Using the geology of Australia, and elsewhere, this project is expected to derive the oxygenation evolution of ancient seawater and its effect on reef ecosystems during critical intervals of Earth's history.
ActivityThe oxygenation of Earth-s early marine ecosystems
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $408,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to advance development of high-performance rechargeable aqueous zinc-air (Zn-air) batteries by engineering the triple-phase boundary to increase battery efficiency and power density for practical applications. There is an urgent need to develop sustainable and efficient energy storage and conversion systems to underpin technological development with increasing demand for superior battery technologies for portable electronics, renewable power sources and electrified vehicles. This project expects to accelerate the commercialisation of rechargeable aqueous Zn-air batteries and progress global commitments to new clean energy sources and storage technologies that are efficient, cost-effective and reliable.
ActivityEngineering triple-phase boundary for superior aqueous metal-air batteries
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $328,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to understand Wolbachia infections across Australian Drosophila flies. Wolbachia bacteria that live inside the cells of insects and other invertebrates are widely seen as a promising tool for pest and disease control. This project will assess the population distribution, host phenotypic effects, population dynamics and evolutionary context of multiple Wolbachia infections across Australian Drosophila flies. The outcome will include new and novel strains for applied projects, new information on the fate of Wolbachia infections, and new insights into the factors that dictate the fate of Wolbachia infections across populations.
ActivityWolbachia endosymbionts: novel strain dynamics in Australian Drosophila
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $553,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to integrate quantum hyperpolarisation technology into state-of-the-art nuclear magnetic resonance (NMR) systems, potentially boosting the signal by several orders of magnitude. Understanding the structure and function of membrane bound peptides and proteins in cells in their native environments is critical in drug development. However, studying these biomolecules by conventional NMR under ambient conditions is challenging due to sensitivity limitations. The technology developed by this project will be a significant step forward in NMR and the new science enabled may have far reaching consequences for the study of peptides and proteins of live cells for the development of new drugs and anti-biotics, with direct societal benefits and flow-on economic benefits.
ActivityIntegrating quantum hyperpolarisation in nuclear magnetic resonance systems
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $485,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to use never-before analysed combinations of datasets and new data on Australian housing conditions to model the consequences of unequal access to housing and housing wealth among Australians, and to evaluate both individual and national benefits of housing interventions across generations. The consequences of unequal access to housing are different for current and future generational cohorts. This project expects to reveal the drivers and health consequences of the intergenerational housing gap. Research-based insights on the intergenerational housing crisis will benefit almost all Australians affected by the unprecedented costs of ownership and renting.
ActivityClosing the housing gap: a spotlight on intergenerational inequalities
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $320,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to investigate the process of lifting objects off the seabed. Understanding this breakout process is the scientific basis for a variety of offshore applications such as oil and gas decommissioning, marine salvage and securing foundations under extreme storms. This project expects to advance the understanding of soil-fluid'structure interactions of this problem using innovative high'speed photography observations and advanced numerical coupled analyses. Outcomes will include a numerical tool, verified against a high quality experimental database, to predict the breakout process and uplift required for pressing offshore challenges. The ability for Australia's engineers to predict lift procedures more accurately will contribute to safer operations in Australian waters and to the more economic harnessing of ocean resources.
ActivityLifting objects off the seabed
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $430,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to develop a new type of single photon detector suitable for applications in quantum communication, sensing and metrology by exploiting recent breakthroughs in the discovery of superconductivity in boron doped diamond. This project expects to demonstrate a new, scalable architecture for integrated photonic circuits using the special properties of diamond which allow single-photon quantum emitters, passive optical components, and single-photon detectors to be integrated into one monolithic diamond chip. Expected outcomes include accelerating the uptake of Australian quantum technologies and strengthening international collaborations. Significant benefits include enhanced advanced materials manufacturing capability. -The project also provides a pathway to increase linkages with companies which are commercialising quantum technologies.
ActivityDiamond superconducting nanowire single photon detectors
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $575,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeMammals have an intricate and highly complex immune system, whose function alters throughout life. Why and how this occurs is very unclear however, yet remains a crucial question. This project aims to provide fundamental knowledge on how the human lifespan shapes specific T cell receptors and determine molecular mechanisms underlying gain-of-function and loss-of-function during immunologically distinct phases of life. This project will provide analysis of multi-dimensional, high throughput datasets to identify fundamental links between the transcriptional landscape and TCR signatures across human lifespan, thus will significantly answer key immunological questions in the field.
ActivityLifespan-dependent molecular shaping of the T cell receptor repertoire
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $420,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to study copper-promoted ubiquitination, a novel discovery that a conserved copper binding site in conjugating enzyme UBE2D2 promotes ubiquitination of a range of proteins including tumor suppressor p53. It predicts a correlation between copper homeostasis and cellular proteostasis and may rationalise an inverse relationship between Alzheimer's disease and cancer. This project will employ a range of integrated approaches to illuminate the molecular nature of this copper action. Expected outcomes include an understanding of the molecular mechanisms of this process, and enhanced interdisciplinary collaboration. Potential benefits include new strategies to intervene in copper-related disorders.
ActivityMolecular study of copper-promoted ubiquitination
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $420,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to develop novel amide-bond forming reactions for the chemical synthesis of peptides and proteins. New peptide ligation strategies, including an asparagine-based ligation and a residue-independent ligation will be developed that exploit the recent discovery of silver-promoted coupling reactions of thioamides. A novel late'stage, chemo'selective assembly of N-glycosylated asparagine residues in peptides and proteins will also be developed. The outcomes of this research will lead to breakthroughs in synthetic methodologies for the assembly and functionalisation of peptides and proteins, thereby enabling access to a range of homogeneous, post translationally modified proteins though total chemical synthesis.-These research outcomes will expand Australia's research capability and global competitiveness in the field of biotechnology, delivering significant benefits to the third largest manufacturing sector in Australia.
ActivityThioamide ligations: new technologies for peptide and protein synthesis
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $339,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to conduct a comprehensive study on density-based clustering to improve data management in parallel computing environments. Clustering, a fundamental task in data management, is to group a set of objects such that objects in the same group (called a cluster) are more similar to each other than those in other groups in order to simplify retrieval of similar information. Clustering is widely used in many fields including machine learning, pattern recognition, information retrieval, bioinformatics and image analysis. It is expected that the developed clustering techniques will provide significant performance improvements in industry sectors where decisions are made based on clustering data analytics, such as the sectors of finance, renewable energy and artificial intelligence.
ActivityHigh performance density-based clustering in parallel environments
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Oct 201930 Sep 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $450,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to build on the discovery of a new titanium structure, and to understand how and why it is formed. Titanium alloys are important engineering materials for their high strength, low density and excellent corrosion resistance. The project is expected to reveal the role of magnesium in stabilising the various metastable titanium structures, by combining well controlled mechanical activation, high resolution characterisation and first-principles calculations. The insight gained is expected to guide the design of a new generation of titanium alloys, benefiting the Australian titanium manufacturing and biomedical industries.
ActivityFace-centred cubic titanium: How is it created and why is it formed-
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $552,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to test the efficacy and evolutionary stability of different types of gene drives, and model whether gene drives can be used to eliminate incursions of Drosophila suzukii into Australia. It is now possible to use genome editing technology to alter populations of organisms using -gene drives-. Multiple strategies have been conceived with a major distinction between those that aim to eliminate populations versus those that aim to modify populations. This project will examine these strategies in two fly species, the model, Drosophila melanogaster and the devastating pest of horticulture, Drosophila suzukii. The project expects to assess a gene drive strategy to control the invasive pest that threatens the Australian soft'skinned fruit industries.
ActivityPotential of gene drives to eliminate incursions of Drosophila suzukii
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $410,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to-develop and apply novel bioanalytical mass spectrometry-based methods and workflows to illuminate the otherwise hidden structural diversity and molecular complexity of the lipidome. The structure of individual lipids define their specific biological functions. A major requirement of analytical methods employed for lipid analysis on a lipidome-wide scale, therefore, is to enable the detailed structural characterisation of the, potentially, tens of thousands of individual molecular lipid species that may be present within a sample of interest. This project will develop and optimise novel, ultraviolet photodissociation-tandem mass spectrometry methods which will be integrated within an automated lipidome analysis workflow, to enable comprehensive global lipidome profiling and to reveal the structural diversity of lipids involved in fundamental cellular signalling processes.
ActivityPhotodissociation mass spectrometry for lipidome analysis
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $395,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to increase the volume of streamed data that can be handled on a low-powered device with limited memory. In finance, health, and transport, data arrives at enormous rates, and data-driven decisions must be made quickly. Likewise, to keep Australia secure, national agencies monitor and gather vast data sets. Increasingly, devices and monitors that have limited resources are making these decisions and they require computational techniques that run extremely efficiently. The project expects to develop and improve approximate data structures that operate in tight resource bounds. Anticipated outcomes are improved event recognition and dramatic speedup in analysis of streams in areas such as finance, health, transport, and urban data.
ActivityApproximate structures for efficient processing of data streams
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $311,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to map and critically analyse the shift towards negotiated enforcement in response to corporate misconduct in the financial sector. There is growing concern within the community, consumer advocates, elected representatives and the finance industry itself about the increasing use by regulators of negotiated enforcement mechanisms rather than litigation to counter serious corporate misconduct in the financial sector. There is concern that these practices may lack transparency, be inefficient, fail to deter corporate misbehaviour, and operate to subvert individual justice and the rule of law. This project aims to address these concerns by developing detailed recommendations for reform based on an examination of the theory and practices of Australian and United States of America financial regulators.
ActivityRegulatory power and corporate misconduct
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $352,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to conduct a comprehensive, cross-case study on the effect of major disasters on the intensity of ongoing armed conflicts. The numbers of natural disasters and of armed conflicts are on the rise, yet little is known about the interactions between both phenomena. This project will study 36 cases of disaster striking armed conflict zones to generate new knowledge natural disaster-related risks. The project will enable more targeted on the ground practices and policy measures in the domains of climate change adaptation, foreign policy, peace building and disaster risk reduction.
ActivityThe impact of disasters on armed conflicts
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Sep 201931 Aug 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $342,411
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to investigate how highly palatable foods that are high in fat and sugar, interact with the brain to cause their overconsumption. Highly palatable foods cause plasticity in brain reward circuitry in a manner similar to drugs of abuse. Identifying how these "junk" foods interact with reward areas of the brain will explore the neural mechanisms underlying the hedonic nature of appetite. This project will not only inform our understanding of how exposure to these foods can contribute to overeating and obesity, a huge and growing problem in Australia, but will also provide evidence to inform policy options relevant to advertising and marketing of these foods.
ActivityUnravelling the relationship between food and the brain
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201804 Dec 201903 Dec 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $370,278
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to investigate whether affirmative action education policies can assist in breaking down social inequality. It will do so by exploring the lived outcomes of India's Right to Education Act, which requires private schools to provide free education for underprivileged children. Based on long-term fieldwork, this project is expected to identify factors that contribute to inclusivity in private schools, and to generate fine-grained data on class contestation. Anticipated outcomes include a deeper understanding of how Indian private schools can be desegregated, new perspectives on the analysis of class globally, and insights into the relationship between the state, the private sector and education as a public good.-The project will inform Australian debates about social mobility and education as a public good.
ActivityTackling social inequality in Indian schools
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201818 Mar 201917 Mar 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $348,070
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to study symmetries which control geometry and physics of four-dimensional manifolds. Representation theory is the area in pure mathematics which studies symmetries coming from geometry, algebra, and physics. The expected outcome is new families of quantum algebra, their character formulas, and a solution to an infinite-dimensional moduli problem. This project will further deepen the mathematical knowledge of symmetries, and show unexpected new connections between different areas of pure mathematics and mathematical physics.
ActivityElliptic representation theory: the study of symmetries across geometry, algebra and physics
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $360,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Early Career Researcher Award
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to investigate the ways in which states, international organisations, and international communities have engaged with the -world ocean- as a natural environment from the 1950s to the 2000s. In the context of current environmental and geopolitical challenges for the ocean, this project will analyse how these actors built institutions, communities, and territories in and for the ocean environment as a foundation for generating knowledge and claiming power, rights, and resources. By understanding the structures and origins of contemporary ocean ideas, spaces, and institutions, this project aims to benefit current efforts to create resilient ocean environments and communities at the international scale.
ActivityAn international environmental history of the 'world ocean', 1950s-2000s
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201818 Dec 201801 Jan 201931 Dec 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $385,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Linkage
Component Linkage Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to develop a prototype of high-density optical interconnects for mobile fronthaul systems using few-mode transmission techniques. This is required to meet the high bandwidth demand from 5G mobile standard, which is to be rolled out worldwide in the near future. The project expects to advance knowledge of space-division-multiplexing techniques using cost-effective direct detection. The methodologies and technologies developed through this project will enhance the competitiveness of the Australian's telecommunication sector, especially on the deployment of 5G services to the broader community. This technology will be critical to Australia's digital economy, from supporting virtual reality to autonomous driving and will provide significant benefits to the Australian optical communication industry.
ActivityHigh-density mobile fronthaul optical interconnects using few-mode fibers
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201830 Apr 201922 May 201921 May 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $207,497
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Linkage
Component Linkage Projects
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to develop an order processing capability that eliminates execution risk underlying portfolio rebalancing in financial markets. The proposed market design is expected to lower transaction costs for investors, lower funding costs for firms and governments and enhance liquidity in markets that are naturally thin. The market design is expected to have a significant impact on an economy like Australia's, which through its superannuation savings system depends on well-operating financial markets for savings and investments. The project is expected to result in lower costs of funding for firms and government, benefitting employment and the enhancement of Australia's expertise in fintech and its capacity to export cutting-edge financial information technology.
ActivityContinuous combinatorial order processing In financial markets
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201830 Apr 201924 Dec 201923 Dec 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $430,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Linkage
Component Linkage Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to establish the capability to manufacture application'specific semiconductor lasers. The project will use existing facilities in Australia to enhance our world-leading quantum science research, and establish a viable export-dominated high-tech manufacturing business. Semiconductor lasers are a critical enabling technology for many scientific applications, particularly for quantum science including quantum computing and quantum sensing. This project is expected to enable the establishment of a high-tech manufacturing capability to support Australia's leading role in quantum science, and expand our scientific instrumentation exports to new and rapidly developing applications such as magnetic sensing and imaging at nanoscale, quantum communication and computation.
ActivityHigh-brightness wavelength tuneable lasers for quantum science
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201830 Apr 201929 Aug 201928 Aug 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $450,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Linkage
Component Linkage Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeAnimal stress has substantial implications on animal productivity, health and welfare of farm animals and thus farm profitability. This project aims to examine the stress resilience in pigs. Modern pig farming is a major source of food, providing substantial nutritional, social and economic benefits in Australia and worldwide. Animal welfare is of increasing concern to the public, consumers and pork producers, and stress vulnerability is an animal health and production problem in the life of the commercial pig. This project will generate new knowledge on early life management to endow stress resilience in pigs, with expected benefits for animal welfare, farm productivity and profitability.
ActivityEarly stress experiences and stress resilience in pigs
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201830 Apr 201924 Dec 201923 Dec 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $222,782
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Linkage
Component Linkage Projects
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to road-test, document and analyse an innovative strategy for amplifying Indigenous voices in news media. The project will deploy and assess the impact of a new digital application designed to enable access to a diverse range of Indigenous voices, stories and agendas. The anticipated outcomes will assist the project's industry partners meet their strategic goals of increasing the level of Indigenous media representation in Australia, and consolidate their roles as leading outlets for Indigenous content and coverage. These outcomes are also expected to improve public understanding of issues affecting Indigenous Australians and contribute to more informed and inclusive policy discussions.
ActivityAmplifying Indigenous news: a digital intervention
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201830 Apr 201924 Dec 201923 Dec 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $297,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Linkage
Component Linkage Projects
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeThis project aims to develop an innovative, Australian'specific multidimensional measure of gender equality. The project's focus on conceptualising and measuring gender equality in the Australian context will address a significant barrier to the development, implementation and evaluation of targeted gender equality programs and policies. By partnering with government and industry representatives, this project will develop a baseline from which programs and policies can be measured. The project will also establish evidence about the effects of gender equality in relation to economic, social and wellbeing outcomes.
ActivityGender equality in Australia: impact on social, economic and health outcomes
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Nov 201830 Apr 201924 Dec 201923 Dec 2022 2018-19
UNIVERSITY OF MELBOURNE
Melbourne  $479,375
Address Melbourne 3000 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency Cancer Australia
Program Improved cancer control
Component 2018 Priority-driven Collaborative Cancer Research Scheme
CategoryCancer Targeted or Restricted Competitive
PurposeSurvivors of colorectal cancer (CRC) can experience distressing problems after treatment. Most people are followed-up by specialists at busy hospital clinics, however this model does not meet the needs of many patients, and is unsustainable due to growing patient numbers. A shared-care model of follow up with specialists and general practitioners may be as effective, cheaper and preferred by patients. The proposed study is the first internationally to rigorously evaluate shared-care for survivors of CRC.
ActivitySCORE: Shared care of Colorectal cancer survivors - A randomised controlled trial of hospital-based follow up versus shared hospital / general practice follow up for survivors of colorectal cancer (CRC)
Delivery Area Multiple National AUSTRALIA
ApprovedPublishedStartEndBudget
27 Mar 201902 Jul 201901 Apr 201931 Mar 2022 2018-19
UNIVERSITY OF MELBOURNE
Melbourne  $44,000
Address Parkville 3010 VIC AUSTRALIA ABN: 84002705224
Portfolio Infrastructure and Regional Development
Agency Department of Infrastructure, Regional Development and Cities
Program Surface Transport
Component Australian Michigan Mobility Summit
CategoryTransport
PurposeThe purpose of the grant is to support the University of Melbourne in hosting a workshop under the auspices of a transport Memorandum of Understanding (MOU), signed by the Australian Government and the Government of the State of Michigan in October 2018. This workshop will support the Commonwealth in its attempts to realise the benefits of transport technologies such as connected and automated vehicles, with a focus on improving transport network and road safety outcomes.
ActivityThe Commonwealth will provide financial support to the University of Melbourne for activities undertaken to prepare for the transport technology workshop.
Delivery Area 3000 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Jun 201915 Aug 201913 Aug 201915 Oct 2019 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $1,500,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency Department of Health
Program Health policy Research and Analysis
Component Accelerated Research
CategoryMedical Research Open Competitive
PurposeAccelerated Research
ActivityAccelerated Research
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Feb 201829 Aug 201823 Jul 201816 Apr 2019 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $573,689
Address UNIVERSITY OF MELBOURNE 3010 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency Department of Health
Program Health policy Research and Analysis
Component Accelerated Research
CategoryMedical Research Open Competitive
PurposeAccelerated Research
ActivityAccelerated Research
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Feb 201808 May 201924 Apr 201930 Jun 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $384,526
Address UNIVERSITY OF MELBOURNE 3010 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency Department of Health
Program Health policy Research and Analysis
Component Accelerated Research
CategoryMedical Research Open Competitive
PurposeAccelerated Research
ActivityAccelerated Research
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
27 Feb 201808 May 201924 Apr 201930 Jun 2022 2018-19
UNIVERSITY OF MELBOURNE
Melbourne  $1,071,602
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Targeted Research
CategoryMedical Research Targeted or Restricted Competitive
PurposeDSCATT (Debilitating Symptom Complexes attributed to Ticks) are medically unexplained. With similar conditions, effective therapies have been developed even though the causes are unclear. This project would extend that approach to DSCATT. We would first develop a case definition, then adapt the treatment approach for unexplained syndromes to the specifics of DSCATT. We would then pilot a randomised controlled trial to confirm the effectiveness of the new therapy.
ActivityGNT1169827 | Developing Treatment for Debilitating Symptom Complexes attributed to Ticks
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
26 Nov 201818 Apr 201901 Feb 201931 Jan 2024 2018-19
ASIALINK BUSINESS
Melbourne  $528,900
Address PARKVILLE 3006 VIC AUSTRALIA ABN: 84002705224
Portfolio Foreign Affairs and Trade
Agency Department of Foreign Affairs and Trade
Program New Colombo Plan
Component New Colombo Plan
CategoryPublic Diplomacy
PurposeThe Grant activity is the New Colombo Plan (NCP) Alumni Grant including the NCP Alumni Ambassadors Project and Professional Development activities and opportunities.
ActivityAlumni
Delivery Area Multiple National AUSTRALIA
ApprovedPublishedStartEndBudget
26 Jun 201816 Jul 201826 Jun 201830 Jun 2020 2018-19
UNIVERSITY OF MELBOURNE
Melbourne  $8,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Industry, Innovation and Science
Agency Department of Industry, Innovation and Science
Program Supporting Science and Commercialisation
Component Science for Australia's Future - Inspiring Australia
CategoryScientific Research Open Competitive
PurposeThe lid has been lifted on human wastefulness, but what next- Science Gallery Melbourne (SGM) delves into our ever-growing mountain of garbage to find innovative opportunities and solutions. In 2018 a research group in Japan found bacteria that love to feast on plastic. This National Science Week, SGM is teaming up with Bioquisitive to throw down the gauntlet, and challenge Australia to find the next plastic-eating bacteria! This project takes Science Gallery Australia-wide, asking citizen scientists to culture bacteria in the search for a new species that could solve our plastic waste dilemma. SGM is part of an international network, engaging 15-25 year olds with STEM through the collision of art and science. Join the team trying to find Australia's Next Top Plastic Eating Bacteria.
ActivityHunt for the plastic eaters, Australia to find solution to plastic waste dilemma
Delivery Area 3010 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
26 Feb 201903 Apr 201929 Mar 201929 Feb 2020 2018-19
UNIVERSITY OF MELBOURNE
Melbourne  $85,650
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Postgraduate Scholarships
CategoryMedical Research Targeted or Restricted Competitive
PurposeThis projects seeks to achieve deeper understanding of the driving biology of advanced and lethal prostate cancer by way of profiling the tumor genes of patients with the disease. By doing so, we will be able to identify the gene mutations that occur in aggressive prostate cancer and how they influence response to treatment and clinical outcomes. We may be able to incorporate this information to deliver more informed, -precision- care to patients in the future.
ActivityGNT1169594 | Somatic genomic alterations as predictors of clinical outcomes and benefit from chemohormonal therapy in metastatic hormone sensitive prostate cancer
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2020 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $96,294
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Postgraduate Scholarships
CategoryMedical Research Targeted or Restricted Competitive
PurposeBreast cancer is the most commonly diagnosed cancer in females in Australia and its incidence continues to increase. There is emerging evidence that immune cells play an important role in fighting particular subtypes of breast cancer (HER2-positive and triple negative). Currently, there is no immunotherapy available in the treatment of breast cancer. We aim to investigate the role of the immune microenvironment in the treatment of HER2-positive breast cancer.
ActivityGNT1168567 | Investigating the role of the immunity in HER2-positive breast ductal carcinoma in situ and invasive ductal carcinoma and response to HER2 targeted treatment
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Mar 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $96,492
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Postgraduate Scholarships
CategoryMedical Research Targeted or Restricted Competitive
PurposeThe media is a key source of information about mental illness, it has strong potential to reduce stigma towards severe mental illness (SMI) on a widespread scale. My PhD research will investigate the influence of media reporting on stigma towards SMI, gain an understanding of stakeholders- perspectives on and recommendations for media reporting on SMI, develop media reporting guidelines to reduce stigma, and develop and trial a brief intervention based on the guidelines with journalism students.
ActivityGNT1168138 | Mitigating the impact of the media on stigmatising attitudes towards people with severe mental illness
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Jul 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $88,502
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Postgraduate Scholarships
CategoryMedical Research Targeted or Restricted Competitive
PurposeAsthma and COPD are hard to diagnose in early stages, therefore, adversely affect individuals and communities. The main aim of my Ph.D research is to understand the actual association of the lifetime BMI trajectories and asthma and COPD. Also, will assess the association of biomarkers as mediators. These investigations will give an in-depth understanding of the natural course and interaction of these risk factors and diseases, which results in prevention and management of the disease in future.
ActivityGNT1169541 | Association of obesity and metabolic biomarkers with asthma, COPD and lung function both in children and adult population of Melbourne and Tasmania
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $64,057
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Postgraduate Scholarships
CategoryMedical Research Targeted or Restricted Competitive
Purpose2.2 million elective surgeries occur in Australia annually. This study is investigating the economic and environmental impacts of unnecessary routine preoperative pathology testing for patients having elective surgery. It will determine the annual impacts of unnecessary testing at two Victorian hospitals, and will seek to establish whether there are any predictors to the ordering of tests. The aim is to aid in the development of strategies to reduce the impacts of preoperative testing.
ActivityGNT1168276 | Environmental and economic impacts associated with unnecessary routine pathology testing in Victorian public hospitals
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201928 Feb 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $128,225
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Postgraduate Scholarships
CategoryMedical Research Targeted or Restricted Competitive
PurposeUlcerative colitis is a disease that causes damage to the lining of the bowel wall. Twenty percent of patients have a severe form of the condition. A third of patients do not get better with steroids and need infliximab, a stronger medication to help avoid emergency surgery to remove the large bowel. Our study aims to assess whether giving larger or more frequent doses of infliximab improves the chances of patients getting better and avoiding the need for surgery.
ActivityGNT1168602 | Acute severe ulcerative colitis - clinical and translational studies
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $32,279
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Postgraduate Scholarships
CategoryMedical Research Targeted or Restricted Competitive
PurposeDiabetes is a serious health issue. Most people with type 2 diabetes (T2D) also have at least one other long-term condition. This is termed -multimorbidity.- This project will utilise a variety of Australian and international datasets to study associations between multimorbidity, mortality and blood glucose in people with T2D. Results will guide clinical practice and research as to how to improve outcomes for people with T2D.
ActivityGNT1168372 | A Study of Multimorbidity in Type 2 Diabetes: Exploration of Associations between Multimorbidity, Mortality and Glycaemia in People with Type 2 Diabetes.
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Jan 2020 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $96,492
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Postgraduate Scholarships
CategoryMedical Research Targeted or Restricted Competitive
PurposeExperiences in pregnancy, the quality of early parenting, and parenting preparedness are important for both infants and parents. These studies aim to explore first-time parents parenting preparedness and experiences with healthcare providers, and to develop supports, resources and education programs to support healthcare providers and first-time parents outside the current healthcare system, which will be informed by the qualitative data.
ActivityGNT1168793 | How can we better support first-time parents in the transition to parenthood and early parenting-
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Jul 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $128,225
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Postgraduate Scholarships
CategoryMedical Research Targeted or Restricted Competitive
PurposeThis scholarship will fund a PhD position in Respiratory Epidemiology at the University of Melbourne. The doctoral work will examine the lifetime role of asthma in the development of chronic obstructive pulmonary disease (COPD), and aims to evaluate current treatment options and diagnostic criteria in the prevention and early detection of COPD. The overall aim is to reduce the impact of obstructive airways diseases at a population-level in Australia.
ActivityGNT1169042 | Lifetime asthma in the development of fixed airflow obstruction: strategies for prevention and early detection
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $92,746
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Postgraduate Scholarships
CategoryMedical Research Targeted or Restricted Competitive
PurposeAcute kidney injury (AKI) is an abrupt loss of kidney function, and is associated with an increased morbidity, mortality and healthcare costs. The leading cause of AKI is kidney ischemia reperfusion injury (IRI), which is a sudden reduction and subsequent restoration of blood flow to the kidney. This initiates inflammation and cell death. This project aims to better understand the pathways leading to cell death after kidney IRI. By blocking these pathways, we hope to prevent cell death and AKI.
ActivityGNT1168307 | Regulated necrosis in ischemia reperfusion injury.
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201928 Feb 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $84,106
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Postgraduate Scholarships
CategoryMedical Research Targeted or Restricted Competitive
PurposeProblems, or complications, after surgery prolong recovery and hospital length of stay. There is growing interest in preparing people for surgery 'Prehabilitation'. This project will investigate the (1) feasibility and effects of an individualised prehabilitation program for high risk cancer patients within the Australia public healthcare context, (2) patient and general practitioner perceptions of prehabilitation and (3) patient factors that may affect the success of prehabilitation programs.
ActivityGNT1168216 | Prehabilitation in Cancer Surgery
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Mar 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $50,171
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Postgraduate Scholarships
CategoryMedical Research Targeted or Restricted Competitive
PurposeColorectal cancer remains a significant health burden worldwide. The Ramsay Laboratory (Peter MacCallum Cancer Centre, Melbourne) has developed a novel DNA vaccine, TetMYB, that targets the MYB oncogene, which has been shown to be over-expressed in colorectal cancer and adenomatous polyps. Furthermore, the majority of colorectal cancer develop of adenomatous polyps thus targeting these pre-cancerous precursor lesions is a highly effective means of cancer prevention; i.e. the aim of this study.
ActivityGNT1168983 | Novel Vaccine Targeting Colonic Adenoma: A Pre-Clinical Model
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201929 Feb 2020 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $1,727,050
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeAlarmingly, last year more antidepressant (AD) prescriptions were written in Australia than there were Australians. This is because many people keep taking ADs for longer than they need to and often don-t know when or even how to stop. We have developed an online program to help people stop when their GP says it's OK to do so. This Project will test whether our program can help people cease their AD use safely and successfully, thereby reducing costs and adverse health impacts.
ActivityGNT1157337 | STOPS: A randomised trial of a STructured Online intervention to Promote and Support antidepressant de-prescribing in primary care
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2023 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $1,166,576
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeAboriginal children are over-represented in out-of-home care and at every stage of the child protection process. This study will examine I) trends in out-of-home care for Western Australian Aboriginal children born between 2000 and 2013; II) differences in health for children removed compared to those who remain in their parents care; and III) the views and perspectives of kinship carers and staff from Aboriginal primary health care services about how to improve the child protection system.
ActivityGNT1162968 | Predicting and preventing child removals and optimising the child protection system for Aboriginal children in partnership with Aboriginal communities and health services
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $595,394
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeProstate cancer is now the most commonly diagnosed cancer but only 10 percent of men with it, will die from it. Our current ability to discriminate between cancers with an indolent course and those that are lethal is poor. This project will define the genetic changes associated with high risk disease and by linking with other large international studies generate a set of signature changes that can be used to screen the blood of early stage patients and identify those with high risk disease.
ActivityGNT1162514 | The genomic drivers of high risk prostate cancer
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $1,192,127
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeBleeding and low blood pressure are common and dangerous complications of anaesthesia and surgery. We propose a large international study to determine if tranexamic acid (TXA) is a safe and efficacious drug to prevent bleeding, and whether preventing low blood pressure is efficacious in reducing death and major complications after surgery in older sicker patients having major noncardiac surgery. This study has the potential to improve clinical outcomes for millions of patients worldwide
ActivityGNT1162362 | Tranexamic acid and hypotension-avoidance to prevent death and major complications after noncardiac surgery (PeriOperative ISchemic Evaluation-3 - the POISE-3 Trial)
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2023 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $765,117
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeHigh levels of immune infiltrate in breast cancers has been shown to be associated with improved survival. It is unknown if simply quantity dictates prognosis or if there are important qualitative differences. We have identified a specific T cell immune subset that we believe is critical to anti-tumour immune responses. This project will delineate this population in greater detail as well as understand the cues that attract and draw in this critical immune population into breast cancers.
ActivityGNT1162318 | Tissue resident memory T cells- delineating their role in breast cancer anti-tumor immunity
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $477,034
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeBirth asphyxia is a leading cause of cerebral palsy, seizures, developmental delay and death in term babies. Current methods of detecting fetal distress are inaccurate and can be misinterpreted. In this project we are using new technology to develop a device to continuously assess fetal pH, a direct measure of fetal stress in labour. We will validate our sensor using neonatal cord blood at delivery and assess the accuracy of our device using a fetal sheep model of hypoxia.
ActivityGNT1159585 | Developing a novel device to accurately assess fetal distress in labour
Delivery Area Multiple VIC, SA, Overseas AUSTRALIA, NEW ZEALAND
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $670,788
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeEffective therapeutics are urgently required to combat skeletal muscle seating associated with chronic disease and aging. This project will conduct a series of studies to establish validity for a novel class of muscle therapeutics designed to prevent the processes that drive protein breakdown in wasting muscles.
ActivityGNT1156562 | Developing a novel class of therapeutics for muscle wasting and frailty
Delivery Area Multiple NSW, VIC, WA, Overseas AUSTRALIA, ITALY
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $1,260,040
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeThe lymphatics are an understudied vessel system that is already known to be involved in key aspects of human physiology and disease. In this proposal we will characterise molecules and signalling pathways involved in controlling the formation of new lymphatic vessels and the remodelling of existing vessels via lymphatic endothelial cells that line these vessels. This information will enable us to identify new biomarkers and therapeutic targets to treat human disease.
ActivityGNT1156623 | Defining the heterogeneity of signaling networks that drive remodeling of lymphatic vessels in human diseases
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $899,086
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeAnxiety disorders are extremely debilitating, and are most likely to have their onset in young people. Understanding the biological mechanisms that increase risk for anxiety in this population is critical. This research will, for the first time, investigate the biological mechanisms of -fear extinction- (a key process underlying anxiety) in young people. The results of this project will inform the development of more targeted and effective treatments for anxiety disorders.
ActivityGNT1163499 | Neural mechanisms of anxiety across development and sex
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $4,880,484
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeOur laboratory research confirms clinical observations that gas anaesthetics increase the risk of cancer relapse. We propose a large, international, randomised trial to answer the important question of whether anaesthesia impacts long-term cancer-free survival in patients having cancer surgery. Our clinical trial will research whether an alternative widely used intravenous anaesthetic (propofol) and a common pain medicine (lidocaine) reduces inflammation and thereby stops cancer relapse.
ActivityGNT1160191 | Volatile Anaesthesia and Perioperative Outcomes Related to Cancer (VAPOR-C Trial)
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2023 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $1,233,862
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeSmall babies contribute disproportionately to stillbirth, yet existing methods mostly fail to detect the fetus that is not growing well. We have previously identified markers of placental health that can be detected in the maternal blood in late pregnancy. We have also identified a new method of assessing blood flow to the placenta and the baby. Both of these new assessments seem to improve detection of the small fetus, and we hope to confirm these findings in a further 2000 women.
ActivityGNT1160711 | Using Biomarkers and Ultrasound in late pregnancy to Minimise Preventable Stillbirth: the BUMPs study
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $794,872
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeA patient with colorectal cancer that has spread to other parts of the body has only a 12 percent chance of surviving, as these secondary tumours often regrow once treatment stops. This is due to cells that can resist or adapt to drug treatments within each tumour. Our project aims to better identify which tumour cells can drive post-treatment regrowth and to characterise the different mechanisms underlying this ability - to ultimately prevent post-treatment regrowth improve patient survival.
ActivityGNT1164081 | Characterising mechanisms that underpin drug tolerance and treatment resistance in colorectal cancer metastases.
Delivery Area Multiple VIC, Overseas AUSTRALIA, FRANCE
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $674,920
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeAlzheimer's disease results from toxic peptides arising from the cleavage of a large molecule called APP in the brain. The production of toxic peptides is normally regulated by the transport of APP molecules between compartments inside the cell. In Alzheimer's disease, the APP transport pathways are altered leading to high levels of toxic peptide.This research will discover the basis for the altered transport of APP in disease, information which could allow new approaches for dementia treatment.
ActivityGNT1163862 | Defining the anterograde and endocytic trafficking pathways in primary neurons; relevance to dysfunctional trafficking of BACE1 and APP in Alzheimer-s disease
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $737,192
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeMycobacterium tuberculosis (MTB) infects one third of the global population, with 10.2 million new cases of TB and 1.1 million million deaths in 2015. This study aims to identify antibodies that target MTB from people that naturally control MTB infection for use as monoclonal antibody therapeutics. We will also identify the immune signals required to induce these protective antibodies. Ultimately, this study will guide the development of future MTB vaccines, therapeutics and diagnostics tools.
ActivityGNT1163790 | Identification of functional antibodies that control Mycobacterium Tuberculosis
Delivery Area Multiple VIC, Overseas AUSTRALIA, CANADA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $446,914
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeRandomising patients to receive either an 'active' or a 'sham' (pretend) surgery and comparing the outcomes is the best way to test how effective a surgical procedure is. However, few orthopaedic surgeries have been tested in this way. This study aims to determine the feasibility of conducting a sham surgery trial in a major orthopaedic procedure by 1. identifying the conditions under which patients and surgeons would consider participating 2. Estimating how much it would cost.
ActivityGNT1163613 | The PRETEND Trial: A mixed methods study evaluating PREferences, feasibiliTy, and costs of pErformiNg sham surgery Trials involving major surgical procedures
Delivery Area Multiple NSW, VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2020 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $868,235
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeHip osteoarthritis is a common painful condition, often making activities of daily living difficult. Although strengthening lower limb-muscles can provide some pain-relief-and ease with activities of daily living, many still suffer with unacceptable pain and difficulty with physical function. We will determine if adding aerobic exercise to strengthening exercise will provide greater pain-relief and physical function improvement-compared to strengthening alone in people with hip osteoarthritis.
ActivityGNT1159045 | Strengthening exercise or combined strengthening and aerobic exercise for hip osteoarthritis: a randomised clinical trial
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $976,560
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeTuberculosis, typhoid fever and influenza continue to kill millions of people. These infections are caused by pathogens that hide from the immune system inside host cells. Our studies examine the mechanisms that allow the immune system to evict these pathogens from cellular 'hide-out'. This project will advance our basic understanding of the immune system and will identify targets for novel therapies that are desperately needed in fights against these global killers.
ActivityGNT1159658 | Understanding and exploiting how different cell death pathways control intracellular infections
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $572,182
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeSchizophrenia is a complex disorder with devastating consequences to those that experience it. Despite over a century of research we are still not clear what biological factors influence the disorder. This research will investigate the role of a specific component of the immune system, called complement proteins, in the blood and brain of schizophrenia patients and how they impact patient outcomes. This research will improve our understanding of the biological factors involved in schizophrenia.
ActivityGNT1159674 | The complement cascade, cortical thinning and the development of psychosis
Delivery Area Multiple NSW, VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $387,192
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeState-of-the-art personalised seizure prediction algorithms will be developed to alleviate the stress associated with the unpredictability of epileptic seizures. These algorithms will be designed to run on portable or implanted devices that record brain activity and look for specific signal changes that are predictive of an individual patient's seizures. Warnings would then be given to patients so they can move to safety or a device could be activated to prevent seizures from occurring.
ActivityGNT1160815 | Personalised Seizure Prediction
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $546,890
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeWe have found that a naturally occurring mucin molecule, called MUC13, protects the cells lining the bowel wall from death under stress. Colon cancer cells retain MUC13 and use it to protect them from chemotherapy, biological therapy and immunotherapy. In this project we aim to further understand the cellular mechanisms underlying MUC13's action and focus on capitalising on this knowledge to develop new therapies for colon cancer.
ActivityGNT1164141 | Targeting MUC13 to Sensitise Colorectal Cancer to Therapy
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $679,920
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeImmune checkpoint inhibitor (ICI) therapies boost the immune response against cancer cells and have been very effective in treating certain types of cancer. Unfortunately not all cancers respond to ICIs and a common cause of resistance is failure to express a molecule called MHC class I, which allows the tumour to hide from immune cells. This project will identify ways to restore MHC class I to the surface of resistant tumours to promote elimination by the immune system following ICI therapy.
ActivityGNT1164054 | Restoring MHC class I antigen presentation to enhance anti-tumour immunity
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $707,372
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeA new frontier in biomedical research will involve watching individual proteins work in real time, in living organs. Here, we will investigate the Hippo signalling pathway, which is an important regulator of organ growth and is mutated in many human cancers. We will monitor the movement of different Hippo pathway proteins, in cells of growing Drosophila organs, in real time. This will provide novel insights into normal organ growth and pathogenic organ growth in diseases such as cancer.
ActivityGNT1157737 | Examination of Hippo signalling in real time, in vivo
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $522,521
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposePathogen genomics is increasingly used in public health labs for routine surveillance of notifiable infectious diseases, particularly foodborne and sexually transmitted illnesses. This approach is well established for outbreak investigations, helping epidemiologists to identify sources of infection and disease transmission to guide interventions. This project aims to develop new methods to harness the power of routine genomics data to detect outbreaks earlier and intervene sooner.
ActivityGNT1157586 | A statistical framework to exploit routine pathogen genomics data for public health
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $985,472
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeThe expanding repertoire of treatment options in lung cancer is bringing into focus the need for improved ways to accurately monitor treatment responses and guide treatment decisions. Many cancers shed small amounts of DNA (ctDNA) into the bloodstream and changes in ctDNA levels have potential to be used as specific markers of response to cancer therapy. This project will evaluate novel strategies to directly guide treatment decisions in patients with lung cancer.
ActivityGNT1158345 | Monitoring evolutionary trajectories in non-small cell lung cancer to improve treatment outcomes
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $755,528
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeThe stentrode is an implanted endovascular stent recording electrode that records brain signals from the motor cortex. Through the use of computer algorithms, the device is intended to translate brain signals to a computer interface that enables patients with paralysis to directly control assistive technologies including computer software, robotic upper limb prostheses, and motorized wheelchairs.
ActivityGNT1161108 | STENTRODE WITH THOUGHT CONTROLLED DIGITAL SWITCH: A first in human early feasibility study of the stentrode in participants with loss of motor function due to paralysis
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2020 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $574,920
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeCells use molecules on their surfaces to communicate with other cells and their environment. 'MARCH' proteins are switches that instruct molecules to stay or leave the cell surface and control which molecules are displayed and how many. This project will identify how MARCH play important and unexpected roles in the immune response and in fighting infection to virus.
ActivityGNT1161101 | MARCH ubiquitin ligases in immunity and infection.
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $697,802
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeNeural deficits such as Parkinson's disease can be helped by electrically stimulating the brain to activate neurons. Current implants require an invasive craniotomy, where a hole is cut in the skull and electrodes are implanted in the brain, causing permanent damage. We have designed a new way to implant electrodes through blood vessels and a simple puncture into the jugular vein that removes the need for a craniotomy. We will test the efficacy of this device in stimulating neurons.
ActivityGNT1158912 | Minimally Invasive Endovascular Neural Stimulation
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $832,521
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeThe major problem for type 2 diabetes patients is an inability to control their blood glucose levels, and high blood glucose levels cause the life-threatening complications associated with this disease. We have recently discovered a protein that reduces blood glucose levels. The aim of this project is to determine the long-term effectiveness of this protein and to develop more active forms of the protein. This will improve the management of diabetes.
ActivityGNT1156508 | Regulation of glycemic control by secreted modular calcium-binding protein 1
Delivery Area Multiple VIC, Overseas AUSTRALIA, CANADA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $859,130
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeMulticellular organisms possess different specialised cells with different gene products in different cell types. Much of this specialisation is due to alternative processing (splicing) of gene transcripts. We have recently described the same phenomenon in unicellular parasites. We will now test how alternative splicing drives cellular differentiation to generate specialised parasite forms that infect mosquito vectors, and forms that cause latent, untreatable infections.
ActivityGNT1165354 | Regulation of stage differentiation in apicomplexan parasites by alternative splicing
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $827,362
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeAge-related macular degeneration (AMD) is the most common cause of blindness in Australia, although there few effective treatments. Without fresh understanding into its underlying cause, its incidence is expected to double by 2030. This research will lend new insight into how innate immune pathways drive noxious inflammation in AMD, which will help guide the development of novel antiinflammatory therapeutics to help ease its socio-economic burden on Australians.
ActivityGNT1165599 | Macrophages as novel targets for ameliorating deleterious complement activation in retinal degeneration
Delivery Area Multiple ACT, VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $1,527,368
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeThis proposal is aimed at improving the clinical benefit of BRAF/MEK and CDK4 inhibitors by combining with PRMT5 inhibition and extending these combination therapies into cancers with poor outcomes (pancreatic and oesophageal). These studies will provide mechanistic insight into the action of PRMT5 inhibitors in RAS/RAF/CDK4 driven tumours and identify patients that will likely benefit from PRMT5 therapy including combination therapy.
ActivityGNT1158190 | Inhibition of PRMT5 as a cancer therapy
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2023 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $475,394
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeResponse to therapy varies greatly among patients with multiple sclerosis (MS). The current lack of individualised MS therapy may lead to suboptimal MS management and accumulation of preventable disability. We will use MSBase, the largest international MS cohort, and several international cohorts, to build an algorithm that will enable physicians to identify the best treatment for individual patients with MS at any given time.
ActivityGNT1157717 | Biomarkers to prevent disability in multiple sclerosis
Delivery Area Multiple NSW, VIC, TAS, Overseas AUSTRALIA, CZECH REPUBLIC, SWEDEN, SWITZERLAND
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $1,244,128
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeExercise is the corner'stone of management for people with knee osteoarthritis and is typically provided by physiotherapists during face-to-face consultations. This study will compare the effectiveness of video consultations with physiotherapists to traditional face-to-face consultations by evaluating clinical outcomes, patient and therapist acceptability, and the costs of delivering care with these two approaches.
ActivityGNT1157977 | Technology versus tradition: a non-inferiority trial comparing video to face-to-face consultations with a physiotherapist for people with knee osteoarthritis
Delivery Area Multiple VIC, QLD, Overseas AUSTRALIA, UNITED KINGDOM
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $784,418
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeThe risk that H5N1 -bird flu- viruses will spread around the world in a pandemic has been a concern since they first emerged in humans. They are now widespread in birds and have caused 860 human infections and 454 deaths around the world. Recently H5 viruses have changed and are mixing more freely with other flu viruses in nature. This project will examine why these changes have occurred and will strengthen public health efforts to prepare for future influenza pandemics.
ActivityGNT1156445 | IDENTIFICATION OF MOLECULAR FACTORS THAT INFLUENCE REASSORTMENT AND PANDEMIC POTENTIAL OF HIGHLY PATHOGENIC AVIAN INFLUENZA H5 VIRUSES
Delivery Area Multiple VIC, Overseas AUSTRALIA, UNITED STATES
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $1,518,199
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeInvasive fungal infections are the most serious infection complication in the treatment of haematological cancers such as leukemia, and in solid organ transplants. Not only are there limited antifungal drug choices available, there are emerging resistant fungal infections being reported worldwide. This project aims to establish a national invasive fungal infection surveillance program in high risk patients, and to implement a national program to monitor judicious use of antifungal drugs.
ActivityGNT1156426 | Meeting the challenges of invasive fungal infection: antifungal stewardship and effective surveillance in high risk patient groups
Delivery Area Multiple NSW, VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $1,273,624
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeSevere infections, trauma or stroke cause Systemic Inflammatory Response Syndrome (SIRS). SIRS patients often succumb to otherwise innocuous infections because SIRS induces a long state of immune suppression. We think an underlying mechanisms is the functional impairment of a critical immune cell type called dendritic cells (DC). The goal of this grant is to develop tools to measure, predict and prevent the formation of these 'paralysed DC' to restore a healthy immune system in SIRS patients.
ActivityGNT1163090 | Functional impairment of mouse and human dendritic cells following Systemic Inflammatory Response Syndrome (SIRS): towards novel diagnostics and treatments
Delivery Area Multiple VIC, Overseas AUSTRALIA, FRANCE
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $802,836
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeCurrent influenza vaccines elicit poor protection against viruses undergoing rapid change. We will define the conserved sites of vulnerability on the hemagglutinin of influenza B viruses and use this information to develop and assess novel influenza vaccine concepts in animal models of human influenza infection.
ActivityGNT1162760 | Rational Design of Novel Vaccines for the Control of Influenza B
Delivery Area Multiple VIC, Overseas AUSTRALIA, UNITED STATES
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $997,204
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeProteins are used by cells to control almost all their functions. A key feature of neurodegenerative diseases, like Alzheimer's and Huntington's is that certain proteins abnormally aggregate together which interferes with biological function. This grant seeks to understand why this happens and what the implications are for cellular survival. Gaining this knowledge will aid in the design of therapies combat this abnormality or prevent the damage that is caused by it.
ActivityGNT1161803 | The metastability of proteome foldedness in neurodegenerative disease
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $827,334
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeThis project aims to identify ways in which we can improve treatment outcomes for people with Posttraumatic Stress Disorder. Currently, approximately 40 percent of patients with PTSD do not respond to our first-line treatment, exposure therapy. This project tests if combining exposure therapy with acute exercise leads to better treatment outcomes for people with PTSD, and it tests possible mechanisms underlying this effect.
ActivityGNT1165096 | Improving outcomes from exposure therapy for PTSD with acute exercise: Augmenting Brain Derived Neurotrophic Factor as a mechanism of change-
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $778,386
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeOur body's defense against invading pathogens relies on our immune system. The immune system is made up of multiple cell types that each performs different tasks. In order to function correctly, a family of molecules called inhibitory receptors regulates the immune response. This project will characterize a novel inhibitory receptor axis that we have recently discovered in humans. This may open up new avenues of cancer therapy and autoimmune therapy in the future.
ActivityGNT1165467 | Functional and molecular studies of an interaction between the antigen-presenting molecule MR1 and LILR immune regulatory receptors
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $2,347,015
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeType 1 diabetes (T1D) destroys the insulin-producing cells within the islets of the pancreas, causing blood sugar to rise. Transplantation is the only way to restore normal blood sugar control, but there will never be enough human donors to meet demand. We are pursuing an alternative approach using islets from pigs, which will work well in humans if we can prevent them from being rejected.
ActivityGNT1156889 | Transplantation of pig islets to treat type 1 diabetes
Delivery Area Multiple NSW, VIC, SA AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2023 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $797,151
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeThis work addresses new treatments for brain repair. The innovative nature of this study will lay proof of concept for bioactive scaffolds to be used in brain repair to help promote neural precursor cell migration and facilitating improved functional recovery.
ActivityGNT1156744 | Utilising biomaterials to harness endogenous neural stem cells for brain repair
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $772,521
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeUp to 80 percent of obese individuals have non-alcoholic fatty liver disease. A form of this disease called non-alcoholic steatohepatitis, or NASH, increases the risk of developing advanced liver disease and diabetes. Diagnosing NASH is difficult and relies on taking a liver biopsy, which is invasive and can result in complications. This project seeks to identify biomarkers of NASH from the blood of patients, which will ultimately enable early diagnosis of disease and improved patient care.
ActivityGNT1162511 | Discovery and validation of biomarkers for nonalcoholic steatohepatitis and liver fibrosis
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $593,043
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeAge-related infertility is increasing with profound social and economic implications. Advances in technology and legislation mean that women can elect to freeze their eggs uptake of egg freezing is escalating. Deciding whether to freeze eggs is complex and Decision Aids (DA) are the best way to support informed choice. We have developed a DA for women considering egg freezing and will now test this using a randomised controlled trial
ActivityGNT1163202 | Eggsurance- A randomised controlled trial of a novel Decision Aid for women considering egg freezing
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $812,658
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeMalaria is a major global health issue. Drugs are key weapons against malaria, but resistance typically emerges and spreads, rendering a succession of drugs useless. We recently identified a safe and cheap drug for which the spread of resistance is severely constrained. We propose to identify more such resistance-proof drugs that can be used in combination with other drugs to better manage the spread of resistance and better control disease.
ActivityGNT1162550 | Can we build a genetic trap for drug resistant malaria parasites-
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $480,788
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeGroup A streptococcal (GAS) bacterial infections within the Indigenous populations of Northern Australia are amongst the highest in the world. This project uses genomic analysis, mathematical modelling and experimental evolution to improve our understanding of the role that bacterial recombination - the transfer of genetic material between organisms - plays in the evolution of pathogenic GAS.
ActivityGNT1165876 | Contribution of carbohydrate metabolism to the maintenance of endemic streptococcal pathogens
Delivery Area Multiple VIC, Overseas AUSTRALIA, NORWAY
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $1,399,877
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposePeritoneal cancer develops in the abdomen and may be present at primary diagnosis but can also arise from tumour cells that remain post'surgery or indeed they are mobilized by surgery. It is extremely difficult and expensive to treat and is rapidly fatal compared to most other cancers. We will use genetics, immunology assays, pre-clinical models with national and international collaborations to reduce, treat and cure peritoneal cancer and will test whether we can change clinical practice.
ActivityGNT1156391 | From the Stone Age to the State of the Art - Multidimensional Precision Medicine for Peritoneal CRC
Delivery Area Multiple VIC, SA AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2023 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $854,384
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeCancer arises through the damage to our DNA. Recent advances in technology make it possible now to decode the genetic blueprints of cancers and determine wat drives them. In a pioneering study we identified the common defects driving pancreatic cancer, which is projected to be the 2nd most common cause of cancer death within a decade. We now seek to dig deeper into its triggers of and how it evolves. We also wish to understand the cell types residing and their activity in pancreatic cancer.
ActivityGNT1160855 | Dissecting the mutational landscapes and cellular ecosystems of pancreatic cancer
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $2,766,611
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposePrimary melanomas (PM) are routinely excised with a wide margin to prevent recurrence. For patients with higher risk PM, there is debate as to the extent of the excision margin. We propose a 1cm margin will achieve equivalent survival outcomes to the recommended 2cm margin for patients with higher risk PM, while improving quality of life and reducing costs to the community. This trial will benefit patients worldwide, influencing care, clinical practice and future treatment guidelines.
ActivityGNT1161574 | Melanoma Margins Trial-II: A Phase III, Multi-centre Randomised Controlled Trial Investigating 1cm vs 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma (MelMarT-II)
Delivery Area Multiple NSW, VIC, QLD, Overseas AUSTRALIA, CANADA, SWEDEN, UNITED KINGDOM, UNITED STATES
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2023 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $831,046
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeTo stem the growing epidemic of chronic diseases in rapidly developing countries like India that face significant resource constraints, prevention programs are needed in rural communities where most people still live. Currently, there is very little evidence known about how to do this. Our research team has already evaluated a novel community-based lifestyle intervention to prevent diabetes after 24 months in a high-risk Indian population. We now plan to further assess the outcomes at 7 years.
ActivityGNT1160283 | The long-term effectiveness of a peer-led lifestyle intervention program on diabetes progression and cardiovascular risk: the Kerala Diabetes Prevention Program in India.
Delivery Area Multiple VIC, Overseas AUSTRALIA, INDIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $736,653
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeT cells are dynamic immune cells that protect against infections and tumours. The lymphoid tissues also contain networks of nerves that can control immune responses. Our work has revealed neural circuits that regulate T cell behaviour and changes to the lymphoid tissue nervous system due to infection. This project will use advanced microscopy and innovative tools to determine the neuro-immune interface in lymphoid tissues and reveal new targets to modulate immune responses.
ActivityGNT1161734 | The neuro-immune interface in lymphoid tissues
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $897,551
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeThe body's regulation of breathing and cardiovascular function needs to be matched to maintain optimal functioning of the organism. The brain plays an important role in this regulation. Problems with this interaction play important roles in the development or maintenance of some cardiovascular diseases such as hypertension or heart failure. This grant aims to identify the important neural circuits in order to understand how this interaction is altered in disease states.
ActivityGNT1156727 | Respiratory modulation: Role in the development of cardiovascular diseases
Delivery Area Multiple NSW, VIC, Overseas AUSTRALIA, FRANCE
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $667,192
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeMucosal Associated Invariant T (MAIT) cells are an abundant yet poorly studied type of T cells in humans. Based on our discovery that MAIT cells target pathogens by recognising a by-product of their metabolism, this proposal will identify novel microbial metabolite targets of MAIT cells and provide new insights and approaches to anti-microbial immunity. Thereby this project will deepen our understanding of the biology of MAIT cells and could furnish novel agents to treat microbial infections.
ActivityGNT1157388 | Discovery of novel, microbial antigens recognised by Mucosal Associated Invariant T cells
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $1,020,028
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeDiabetes is an epidemic disease. The major cause of death is due to heart damage and no cardiac specific therapies are available. In this project we investigate the role of glucose-related damage to the proteins which are key in regulating effective heart contraction and pump action and pursue new opportunities to measure these proteins as a blood biomarker of disease. The aim is to advance understanding of disease mechanisms and develop a strategy to diagnose cardiac glucose damage in diabetes.
ActivityGNT1157320 | Diabetic cardiomyopathy - new molecular intervention targets and a biomarker strategy
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2023 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $651,653
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeRheumatoid arthritis is the inflammatory disease's severest form, leading to poor quality of life. This study will investigate the expression and function of two chemokines, CCL17 and CCL22, in the development of arthritis. Using arthritis mouse models and patient samples, I will provide new understanding, not only of how these chemokines are regulated, but also of their role in mediating effector functions. I will comprehensively evaluate their suitability as treatment targets.
ActivityGNT1159901 | REBALANCING THE LEVELS OF CCL17 AND CCL22 TO IMPROVE RHEUMATOID ARTHRITIS
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $829,220
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeThis project will use state-of-the-art molecular biology to understand how the superbug vancomycin-resistant Enterococcus (VRE) colonises patients and spreads in hospitals. The work will identify new targets to allow development of approaches to reduce the burden of VRE in Australian hospitals.
ActivityGNT1160745 | Understanding the mechanisms of gastrointestinal colonisation with vancomycin-resistant Enterococcus faecium (VRE)
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $1,137,742
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeOvarian cancer is the most deadly gynecologic cancer in Western women. Although initially responsive to chemotherapy, drug resistance commonly evolves in a matter of months. We previously documented novel mechanisms of drug resistance in the most common form of ovarian cancer and in this study we will map their distribution within patients. We will also investigate mechanisms of resistance to a new important class of anti-cancer drugs in ovarian cancer, the PARP inhibitors.
ActivityGNT1161198 | Molecular and spatial characterization of drug resistance in human ovarian cancer
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $871,416
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeThis project will identify the role played by the gut's own nervous system in the diarrhoea that is often associated with antibiotic treatment. This type of diarrhoea is common in hospitals and can be fatal if not adequately treated. Understanding the role of the nervous system in this disease process and the changes in nervous system function once diarrhoea is established will point to specific treatments and means of prevention to reduce negative side effects of antibiotic treatment.
ActivityGNT1158952 | Role of the enteric nervous system in antibiotic associated diarrhoea
Delivery Area Multiple VIC, Overseas AUSTRALIA, UNITED STATES
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $614,077
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposePeptide Receptor Radionuclide Therapy (PRRT) is a systematic treatment used to deliver high levels of radiation to cancer using radiopharmaceuticals known as theranostic agents (TAs). Until now TAs have been limited to only a few cancer types. This project aims to develop TAs to treat cancers which overexpress an important molecular target known as Cholecystokinin-2 (CCK-2) receptors. These TAs will be prepared in an innovative manner to display high affinity and stability for CCK-2 receptors.
ActivityGNT1158863 | Development of Innovative Foldamers for the Peptide Receptor Radionuclide Therapy of Tumours Overexpressing Cholecystokinin-2 Receptors
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $900,028
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeNew therapies are required to improve outcomes for patients with ovarian cancer. In this proposal, we will optimise and validate the effectiveness of a new class of drugs we have discovered and developed to selectively damage the DNA of cancer cells, resulting in death of the cancers while sparing normal tissue.
ActivityGNT1162052 | Targeting nucleolar DNA damage response as a novel therapeutic-strategy for high grade serous ovarian cancer
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $612,192
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Project
CategoryMedical Research Targeted or Restricted Competitive
PurposeThis project will combine advanced brain imaging and brain network modelling to understand why people with different anxiety disorders have difficultly regulating fear.
ActivityGNT1161897 | A neural systems model of fear dysregulation in anxiety disorders
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2022 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $707,599
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Boosting Dementia Research Grants
CategoryMedical Research Targeted or Restricted Competitive
PurposeOur project aims to address the need for improved informal care by training cohabitating spouse caregivers (CGs) to implement music interventions (MI) that target behavioural and psychological symptoms of dementia (BPSD), and the quality of life (QoL) and wellbeing of people with dementia (PwD), and of CGs.
ActivityGNT1169867 | A HOME-based Spousal caregiver-delivered music Intervention for people living with DEmentia: A Randomised Controlled Trial
Delivery Area Overseas GERMANY, NORWAY, POLAND, UNITED KINGDOM
ApprovedPublishedStartEndBudget
25 Oct 201821 Dec 201801 Jan 201931 Dec 2021 2018-19
UNIVERSITY OF MELBOURNE
Melbourne  $2,661,502
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Targeted Research
CategoryMedical Research Targeted or Restricted Competitive
PurposeThe Let's CHAT (Community Health Approaches To) Dementia in Indigenous Communities program is a culturally responsive model of care designed to optimise the detection and management of dementia and its precursor cognitive impairment not dementia in Aboriginal and Torres Strait Islander older people attending Aboriginal Primary Care services. This will result in better health outcomes for older people with dementia, their carers and their communities.
ActivityGNT1150337 | Let's CHAT (Community Health Approaches To) -Dementia in Indigenous Communities.
Delivery Area Multiple NSW, VIC, WA, QLD AUSTRALIA
ApprovedPublishedStartEndBudget
25 Mar 201805 Jun 201801 Jun 201831 May 2023 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $88,503
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Postgraduate Scholarships
CategoryMedical Research Targeted or Restricted Competitive
PurposeThis research will explore whether and how sports participation can build social capital, wellbeing and a sense of community for young people from diverse backgrounds across different settings. There is a need for evidence-informed policy regarding the promotion of positive mental health and societal outcomes for this population group and this research will address an identified gap in the literature concerning the specific contextual factors that generate social capital and integration.
ActivityGNT1150326 | -Peering into the black box-: Understanding the contextual factors that generate social capital and promote health and wellbeing for refugee and migrant young people through sports participation.
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
24 Oct 201713 Mar 201801 Jan 201831 Dec 2020 2016-17
UNIVERSITY OF MELBOURNE
Melbourne  $666,281
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Partnership Projects
CategoryMedical Research Targeted or Restricted Competitive
PurposeYouth suicide is a significant problem. This school-based project represents a partnership with the Department of Education and Training and Lifeline. It aims to reduce suicide risk, improve identification of at-risk youth, and increase help'seeking and health service use. It combines educational workshops, case detection, and online treatment. The program will be tested among high school students across North West Melbourne and if effective rolled out nationally via Lifeline's networks.
ActivityGNT1153051 | An integrated response to suicide risk among secondary schools: A regionally-based randomised trial
Delivery Area Multiple VIC, Overseas AUSTRALIA, NEW ZEALAND
ApprovedPublishedStartEndBudget
24 Apr 201805 Jun 201801 Jun 201831 May 2023 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $1,196,362
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Partnership Projects
CategoryMedical Research Targeted or Restricted Competitive
PurposeEach year, 600 Australians are born with cerebral palsy. Despite most cases of cerebral palsy resulting from an injury to the developing brain prior to or around the time of birth, only 26 percent of infants get an early diagnosis before 6 months, delaying treatment and prevention of secondary complication. Early diagnosis of cerebral palsy enables earlier intervention and prevention of complications. This partnership grant ultimate goal is to reduce the age of cerebral palsy diagnosis in Australia.
ActivityGNT1152800 | Early diagnosis and early intervention for infants with cerebral palsy: implementation of international evidence-based guidelines into practice
Delivery Area Multiple ACT, NSW, VIC, QLD AUSTRALIA
ApprovedPublishedStartEndBudget
24 Apr 201805 Jun 201801 Jun 201831 May 2023 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $478,079
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Partnership Projects
CategoryMedical Research Targeted or Restricted Competitive
PurposeWomen vary enormously in their risk of breast cancer, but screening and prevention programs in Australia and across the world have largely ignored this despite new strong risk factors being identified in the last few decades. We are developing better risk measures based on genetics, mammograms and family history. We are making new and improved risk prediction tool (BRISK) widely accessible to women, and to their health providers, on the Internet.
ActivityGNT1153578 | Taking Breast Cancer Risk Prediction to the Next Level and Making it Accessible
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
24 Apr 201805 Jun 201801 Jun 201831 May 2021 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $1,499,594
Address Parkville 3052 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency National Health and Medical Research Council
Program Health and Medical Research
Component Partnership Projects
CategoryMedical Research Targeted or Restricted Competitive
PurposeBuruli ulcer is an ulcerative skin disease caused by the bacterium, Mycobacterium ulcerans. Buruli ulcer cases have been increasing alarmingly around the bayside suburbs of Melbourne and Geelong in Victoria. Here a cluster randomized intervention study will target mosquitoes in affected areas and stop the spread of Buruli ulcer. This project will provide for the first time the urgently needed evidence that will directly inform public health policies to control this emerging disease.
ActivityGNT1152807 | Controlling Buruli ulcer in Victoria
Delivery Area Multiple ACT, VIC AUSTRALIA
ApprovedPublishedStartEndBudget
24 Apr 201805 Jun 201801 Jun 201831 May 2020 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $200,411
Address Parkville 3010 VIC AUSTRALIA ABN: 84002705224
Portfolio Communications and the Arts
Agency Department of Communications and the Arts
Program Arts and Cultural Development
Component Indigenous Languages and Arts Program
CategoryHumanities Open Competitive
PurposeTo preserve and revitalise the Gunditjmara language and dialects of south west Victoria through the creation of 15 songs that will be digitally recorded and available on smart phones and websites as well as featured in public performances.
ActivityRevitalisation of Gunditjmara languages reclamation program
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
23 Jul 201813 Dec 201823 Nov 201830 Jun 2020 2018-19
UNIVERSITY OF MELBOURNE
Melbourne  $349,629
Address Parkville 3010 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency Department of Health
Program Health policy Research and Analysis
Component MRFF Next Generation Clinical Researchers Program Career Development Fellowship
CategoryMedical Research Targeted or Restricted Competitive
PurposeDepression and anxiety disorders are the most prevalent mental illnesses in Australian youth, however current treatments are only modestly effective. In this Fellowship I will lead 5 clinical studies with young people experiencing various illness stages of depression and anxiety. Of these, 3 studies will use a new online treatment delivered via a social media-based internet platform, with a further 2 studies testing new biological (i.e., medication and anti-inflammatory) approaches.
ActivityGNT1158881 - Complex depression and anxiety in youth: Innovative e-therapy and biotherapy clinical trials
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
23 Aug 201831 Aug 201801 Jan 201931 Dec 2022 2018-19
UNIVERSITY OF MELBOURNE
Melbourne  $305,924
Address Parkville 3010 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency Department of Health
Program Health policy Research and Analysis
Component MRFF Next Generation Clinical Researchers Program Career Development Fellowship
CategoryMedical Research Targeted or Restricted Competitive
PurposePreterm birth is the leading cause of newborn deaths worldwide. The smallest, sickest babies are born extremely preterm before 28 weeks' gestation; 50% of survivors develop bronchopulmonary dysplasia (BPD), the chronic lung disease of prematurity. BPD is associated with worse long-term respiratory health and neurodevelopmental outcomes. My research aims to increase survival and reduce morbidity in preterm infants by finding new therapies to prevent BPD, and improving early respiratory supports.
ActivityGNT1159225 - Optimising Respiratory Therapies to Improve Outcomes for Preterm Infants
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
23 Aug 201831 Aug 201801 Jan 201931 Dec 2022 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $535,000
Address UNIVERSITY OF MELBOURNE 3010 VIC AUSTRALIA ABN: 84002705224
Portfolio Health
Agency Department of Health
Program Health Workforce
Component Health Workforce Development
CategoryPublic Health Services Open Competitive
PurposeProvides funding for workforce projects that promote development of the Australian Health Workforce.
ActivityHealth Workforce Development
Delivery Area VIC AUSTRALIA
ApprovedPublishedStartEndBudget
22 Dec 201722 Jun 201801 Jun 201830 Apr 2020 2017-18
UNIVERSITY OF MELBOURNE
Melbourne  $1,100
Address Grattan Street 3010 VIC AUSTRALIA ABN: 84002705224
Portfolio Environment and Energy
Agency Great Barrier Reef Marine Park Authority
Program Portfolio Budget Statements
Component Reef Guardians Research Grants - 2017/18
CategoryScientific Research Open Competitive
PurposeGBRMPA's Reef Guardians Research Grants (previously named Science for Management Awards) are intended to assist students working towards Doctorate or Masters degrees in the physical, biological and social science disciplines, which make a contribution to the management of the Great Barrier Reef Marine Park. Proposed research projects must address GBRMPA's scientific information needs. The awards, under different names, have been in existence for over thirty years.
ActivityReef Guardians Research Grants - 2017/18
Delivery Area 3010 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
21 Nov 201728 Aug 201821 Nov 201731 Jan 2019 2018-19
UNIVERSITY OF MELBOURNE FACULTY OF ENGINEERING
Melbourne  $50,000
Address FITZROY 3065 VIC AUSTRALIA ABN: 84002705224
Portfolio Industry, Innovation and Science
Agency Department of Industry, Innovation and Science
Program Growing Business Investment and Improving Business Capability
Component Entrepreneurs' Programme - Innovation Connections
CategoryIndustry Innovation Demand Driven
PurposeInnovation Connections promotes collaboration between small and medium sized Australian businesses and the research sector to develop new ideas with commercial potential.
ActivityInnovation Connections
Delivery Area 2113 NSW AUSTRALIA
ApprovedPublishedStartEndBudget
21 Mar 201901 May 201901 May 201901 Dec 2019 2018-19
ASIALINK
Melbourne  $128,084
Address Parkville 3010 VIC AUSTRALIA ABN: 84002705224
Portfolio Foreign Affairs and Trade
Agency Department of Foreign Affairs and Trade
Program Public Diplomacy including IRGP grants
Component Austrlia-ASEAN Emerging Leaders Program
CategoryPublic Diplomacy
PurposeThe program brings 15 social entrepreneurs from across our region to participate in an intensive eight day incubator. Working with Asialink at the University of Melbourne, participants will learn new techniques and identify opportunities to scale up, increasing their enterprises' impact. They will also expand their personal and professional networks and build their knowledge of Australian community life.
ActivityBring together young professionals to highlight Australian and Southeast Asian creativity and innovation in social impact and demonstrate the role of business in driving social change
Delivery Area Overseas INDONESIA, SINGAPORE, VIET NAM
ApprovedPublishedStartEndBudget
21 Feb 201927 Mar 201901 Mar 201931 Dec 2019 2018-19
UNIVERSITY OF MELBOURNE
Melbourne  $644,150
Address MELBOURNE 3010 VIC AUSTRALIA ABN: 84002705224
Portfolio Industry, Innovation and Science
Agency Department of Industry, Innovation and Science
Program Growing Business Investment and Improving Business Capability
Component Encouraging Innovation in Advanced Manufacturing
CategoryIndustry Innovation Open Competitive
PurposeFrom Future Fuels to the Future of Transport: The UniMelb AEGP will train graduates in advanced hybrid and electric vehicles, future fuels, Connected Autonomous Vehicles, and advanced material design. We will leverage our existing long'standing relationships with Ford, Toyota and Robert Bosch, and develop new partnerships with SEA Electric and Easymile. The program will not only advance the state-of-the-art in several automotive technologies, but also help lay a foundation for the development of future, automotive transport.
ActivityThe UniMelb Automotive Engineering Graduate Program: From Future Fuels
Delivery Area 3052 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
20 Jun 201928 Jun 201925 Jun 201907 Nov 2021 2018-19
THE UNIVERSITY OF MELBOURNE
Melbourne  $441,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThe project aims to develop new imaging technology for real time recording of electrical activity from cell and neuronal networks with unprecedented resolution and scale. The technology innovation stems from an optical defect in diamond which can be engineered to sensitively detect local changes in electric field. The all-optical diamond optrode array devices will be applied to biological model systems including cardiomyocytes, mammalian cells, and neurons; and will be benchmarked against current state-of-the-art technologies. The knowledge gained from the high density recordings will aid predictive models of disease and will lead to an improved understanding of the brain's micro circuity and functional connectome.
ActivityReal-time neuronal network imaging using diamond optrode arrays
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
20 Dec 201906 Jan 202001 Jan 202031 Dec 2022 2019-20
THE UNIVERSITY OF MELBOURNE
Melbourne  $470,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThe body demands that the heart function at utmost efficiency. Trabeculae folds within the heart lumen maximise blood flow, contribute to chamber development and form the electrical conduction network of the heart. Problems with trabeculae formation cause cardiomyopathy and arrhythmia and yet we do not understand its basic development. The project will investigate the earliest stages of when this tissue develops its identity and examine the signalling, genetic, cellular and extracellular cues required to instruct trabeculae to form in the heart. Findings from this research will revise our understanding of when and how trabeculae form and provide key information about how to grow and repair this important tissue.
ActivityUnderstanding how the heart becomes more efficient
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
20 Dec 201906 Jan 202001 Jan 202031 Dec 2022 2019-20
THE UNIVERSITY OF MELBOURNE
Melbourne  $360,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeHigh data rate communication links between vehicles and surrounding objects are needed to enhance advanced driver assistance systems, enable a wider range of infotainment options and pave the way towards fully automated driving. This project aims to develop a novel framework to use millimeter wave frequencies (the newest candidate for 5G cellular) to enable future high data rate vehicle-to-everything (V2X) communication systems. Based on an innovative approach, the project combines communication and sensor technologies in an integrated system that simultaneously reaps the benefits of autonomously sensing the driving environment and cooperatively exchanging information, thus providing significant savings in hardware costs and spectrum usage.
ActivityMillimeter Wave Frequencies for Vehicle-to-Everything Communications
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
20 Dec 201906 Jan 202001 Jan 202031 Dec 2022 2019-20
THE UNIVERSITY OF MELBOURNE
Melbourne  $230,883
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryHumanities, Arts and Social Sciences (HASS) Research Targeted or Restricted Competitive
PurposeMergers, acquisitions, and collusive conduct take place in imperfectly competitive environments where firms have incomplete information about others. Despite this, standard workhorse models for analyzing the associated competitive effects assume that firms have complete information and typically only accommodate imperfect competition on one side of the market. This project aims to remedy this deficiency by developing the economic theory and associated practical tools for the analysis of competitive effects in settings with incomplete information and market power on both sides. The project work will be presented at seminars and workshops around the globe to both academic audiences and to practitioners at competition authorities.
ActivityIncomplete Information Models for Industrial Organisation
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
20 Dec 201906 Jan 202001 Jan 202031 Dec 2022 2019-20
THE UNIVERSITY OF MELBOURNE
Melbourne  $481,919
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project will develop next-generation focused ion beam microscopy and nanofabrication using a novel cold ion source based on photoionisation of a laser-cooled atom beam. The low temperature and complex internal state structure of the constituent atoms combine to allow generation of ions with unprecedented brightness and resolution. We will use three unique and innovative ideas: field ionisation of atoms in so-called 'exceptional' states to reduce chromatic aberration; electron-ion correlations to enhance control of the ions at the nanoscale; and atom-atom interactions to isolate and manipulate individual ions. The new technology will enable advances in semiconductor nanofabrication and material characterisation.
ActivityAtomic scale ion microscopy via laser cooling and correlated imaging
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
20 Dec 201906 Jan 202001 Jan 202031 Dec 2022 2019-20
THE UNIVERSITY OF MELBOURNE
Melbourne  $611,493
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project aims to discover how microbes dissolve weathering-resistant phosphate minerals that contain valuable rare earth elements used widely in modern technology. This discovery would create new knowledge in the interdisciplinary fields of biogeochemistry and biohydrometallurgy, using an innovative combination of techniques in metagenomics, microbiology and mineralogy. Expected research outcomes include new, more economic and environmentally sustainable biotechnologies for recovering rare earth elements and increasing phosphorus availability in Australian mineral deposits and soils. These outcomes should benefit the mining and agricultural sectors, by decreasing Australia's dependency on overseas REE supply and the use of fertilizers.
ActivityBio-recovery of rare earth elements from Australian soils and mine tailings
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
20 Dec 201906 Jan 202001 Jan 202031 Dec 2022 2019-20
THE UNIVERSITY OF MELBOURNE
Melbourne  $630,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeThis project will investigate superconductivity in silicon nanowire devices exhibiting both p-type and n-type conductivity. It builds on the recent demonstration at the University of Melbourne of superconductivity in nanowire devices at length'scales suitable for realisation of a broad range of superconducting device structures and utilises standard semiconductor-industry processes. This project will create a new platform for superconducting device development in silicon with potential for building devices with new functionality and improved performance for applications in quantum information technologies, enhancing Australia's global reputation in quantum information science and assisting emerging industries in this high-valued added area.
ActivitySuperconducting silicon nanodevices
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
20 Dec 201906 Jan 202001 Jan 202031 Dec 2022 2019-20
THE UNIVERSITY OF MELBOURNE
Melbourne  $360,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeWeb search services have become a fundamental tool used by governments, businesses, and individuals, and play a key role in our access to knowledge and information. In this project we aim to develop new techniques for representing the indexes at the heart of web search services, and to devise new processing algorithms with reduced resource requirements for resolving queries and providing useful and topical answers. Higher query throughput and reduced storage load will benefit providers though reduced hardware and electricity costs, and will benefit society through better access to information, enhanced opportunities to connect and collaborate, and greater long-term scalability as on-line resources continue to multiply.
ActivityEfficient Compression and Querying Techniques for Massive Text Collections
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
20 Dec 201906 Jan 202001 Jan 202031 Dec 2022 2019-20
THE UNIVERSITY OF MELBOURNE
Melbourne  $587,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeCD4+ T (T helper) cells are required to control many important bacterial infections. This Project aims to identify the key targets of CD4+ T cells responding to a model bacterial infection, and to correlate potential antigen effectiveness with native expression, antigen presentation, and the function of antigen'specific CD4+ T cells over time. Our validated experimental 'pipeline' has unprecedented potential to define potent CD4+ T cell antigens within the thousands of proteins expressed by a bacterial pathogen. Our unbiased analysis may help establish the rules that define effective antigenicity. Our work will improve the understanding of bacterial immunity, and inform future design of T-cell based vaccines in the agricultural sector.
ActivityAntigen selection mechanisms control T cell immunity against bacteria
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
20 Dec 201906 Jan 202001 Jan 202031 Dec 2022 2019-20
THE UNIVERSITY OF MELBOURNE
Melbourne  $650,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeEmerging single-cell sequencing technologies are transforming molecular cell biology, but identifying novel cell types and their functions requires the integration of highly heterogeneous data. The development of computational methods able to extract biologically relevant results is hindered by the lack of high-quality datasets. This project aims to develop novel sequencing methodologies and generate data to drive our dimension reduction multivariate method developments for data integration. By combining in silico and in vivo approaches, the project is anticipated to benefit scientists willing to work in cutting-edge single-cell research by providing useful protocols and tools to generate novel insights in cell biology.
ActivityEmpirical and computational solutions for multi-omics single-cell assays
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
20 Dec 201906 Jan 202001 Jan 202031 Dec 2022 2019-20
THE UNIVERSITY OF MELBOURNE
Melbourne  $560,000
Address CARLTON 3053 VIC AUSTRALIA ABN: 84002705224
Portfolio Education and Training
Agency Australian Research Council
Program ARC Discovery
Component Discovery Projects
CategoryScience, Technology, Engineering and Mathematics (STEM) Research Targeted or Restricted Competitive
PurposeAnimals, plants, fungi and bacteria all use pore-forming proteins as cell-killing weapons of mass destruction. Despite their lethal nature and their roles in infection and immunity, how these proteins work remains enigmatic. This project aims to unravel missing molecular details of how a major superfamily of such proteins is able to drill holes in cell membranes. The outcomes could reveal novel mechanisms general to these proteins and provide fundamental insights in understanding vital physiological processes across all kingdoms of life. Ultimately, this knowledge may guide the design of artificial protein pores that are selective for specific molecules with applications such as measuring metal ions, sugars, pesticides or pollutants.
ActivityPore-forming toxins: more than one way to make a hole
Delivery Area 3053 VIC AUSTRALIA
ApprovedPublishedStartEndBudget
20 Dec 201906 Jan 202001 Jan 202031 Dec 2022 2019-20